This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-DNA Polymerase gamma antibody [EPR7296]
catalog :
ab128899
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR7296
reactivity :
human, mouse, rat
application :
western blot
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6f
Silva Pinheiro P, Pardo Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, et al. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021;49:5230-5248 pubmed publisher
  • western blot; mouse; loading ...; fig 4c
  • western blot; human; fig 4a
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  • western blot; human; fig s1d
Akbari M, Keijzers G, Maynard S, Scheibye Knudsen M, Desler C, Hickson I, et al. Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair. DNA Repair (Amst). 2014;16:44-53 pubmed publisher
  • western blot; mouse; fig 2
Douarre C, Sourbier C, Dalla Rosa I, Brata Das B, Redon C, Zhang H, et al. Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism. PLoS ONE. 2012;7:e41094 pubmed publisher
Bajzikova M, Kovarova J, Coelho A, Boukalova S, Oh S, Rohlenova K, et al. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metab. 2019;29:399-416.e10 pubmed publisher
Kauppila J, Bonekamp N, Mourier A, Isokallio M, Just A, Kauppila T, et al. Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res. 2018;46:6642-6669 pubmed publisher
Torregrosa Muñumer R, Forslund J, Goffart S, Pfeiffer A, Stojkovič G, Carvalho G, et al. PrimPol is required for replication reinitiation after mtDNA damage. Proc Natl Acad Sci U S A. 2017;114:11398-11403 pubmed publisher
Sitarz K, Elliott H, Karaman B, Relton C, Chinnery P, Horvath R. Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts. Mol Genet Metab. 2014;112:57-63 pubmed publisher
Gui Y, Xu Z, Lv W, Liu H, Zhao J, Hu X. Association of mitochondrial DNA polymerase ? gene POLG1 polymorphisms with parkinsonism in Chinese populations. PLoS ONE. 2012;7:e50086 pubmed publisher
product information
CatalogNumber :
ab128899
ItemName :
Anti-DNA Polymerase gamma antibody [EPR7296]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR7296
Size :
10 µl, 100 µl
SpeciesSummary :
Hu, Ms, Rat
Application Summary :
WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK