This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Mouse monoclonal [mAbcam12209] to Histone H3 (tri methyl K4) - ChIP Grade
catalog :
ab12209
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAbcam12209
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, ChIP-Seq, blocking or activating experiments
citations: 17
Published Application/Species/Sample/DilutionReference
  • ChIP-Seq; human; ; loading ...; fig 3s3a
Dremel S, DeLuca N. Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s6w
Nagaraj R, Sharpley M, Chi F, Braas D, Zhou Y, Kim R, et al. Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell. 2017;168:210-223.e11 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3c
Itahana Y, Zhang J, Göke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed publisher
  • immunocytochemistry; human
Carmona Mora P, Widagdo J, Tomasetig F, Canales C, Cha Y, Lee W, et al. The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation. Hum Genet. 2015;134:1099-115 pubmed publisher
  • blocking or activating experiments; mouse; 1:200
  • immunocytochemistry; mouse
Huh Y, Sherley J. Decreased H3K27 and H3K4 trimethylation on mortal chromosomes in distributed stem cells. Cell Death Dis. 2014;5:e1554 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 8a
  • western blot; mouse; loading ...; fig 7a
Arnandis T, Ferrer Vicens I, Torres L, García C, García Trevijano E, Zaragoza R, et al. Differential functions of calpain 1 during epithelial cell death and adipocyte differentiation in mammary gland involution. Biochem J. 2014;459:355-68 pubmed publisher
  • western blot; human; 1:1000
Maroschik B, Gürtler A, Kramer A, Rößler U, Gomolka M, Hornhardt S, et al. Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines. Radiat Oncol. 2014;9:15 pubmed publisher
  • chromatin immunoprecipitation; human
Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem. 2013;288:17532-43 pubmed publisher
Liu H, Lin J, Zhou W, Moses R, Dai Z, Kossenkov A, et al. KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer. Cancer Immunol Res. 2022;:OF1-OF11 pubmed publisher
Stengel K, Ellis J, Spielman C, Bomber M, Hiebert S. Definition of a small core transcriptional circuit regulated by AML1-ETO. Mol Cell. 2021;81:530-545.e5 pubmed publisher
Haynes P, Bomsztyk K, Miller D. Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele. Epigenetics Chromatin. 2018;11:47 pubmed publisher
Saha K, Fisher M, Adhikary G, Grun D, Eckert R. Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation. Carcinogenesis. 2017;38:827-836 pubmed publisher
Kataruka S, Akhade V, Kayyar B, Rao M. Mrhl Long Noncoding RNA Mediates Meiotic Commitment of Mouse Spermatogonial Cells by Regulating Sox8 Expression. Mol Cell Biol. 2017;37: pubmed publisher
Janke R, Iavarone A, Rine J. Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases. elife. 2017;6: pubmed publisher
Müller Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, et al. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res. 2015;43:1577-92 pubmed publisher
Mak K, Burdach J, Norton L, Pearson R, Crossley M, Funnell A. Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol. 2014;15:R58 pubmed publisher
Jia J, Parikh H, Xiao W, Hoskins J, Pflicke H, Liu X, et al. An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer. BMC Med Genomics. 2013;6:33 pubmed publisher
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK