Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; loading ...; fig 3e
| Lan P, Fan Y, Zhao Y, Lou X, Monsour H, Zhang X, et al. TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury. J Clin Invest. 2017;127:2222-2234 pubmed publisher
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- western blot; human; loading ...; fig 6e
| Kim M, Song J, Koh D, Kim J, Hatano M, Jeon B, et al. Reciprocal negative regulation between the tumor suppressor protein p53 and B cell CLL/lymphoma 6 (BCL6) via control of caspase-1 expression. J Biol Chem. 2019;294:299-313 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 1c
| Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, et al. Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Nat Commun. 2017;8:2168 pubmed publisher
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- western blot; mouse; loading ...; fig 3b
| Zhang H, Luo J, Alcorn J, Chen K, Fan S, Pilewski J, et al. AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality. J Immunol. 2017;198:4383-4393 pubmed publisher
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- western blot; mouse; loading ...; fig 8
| Hu Z, Zhang Y, Wang J, Mao P, Lv X, Yuan S, et al. Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. Cell Death Dis. 2016;7:e2468 pubmed publisher
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- western blot; mouse; loading ...; fig 5a
| Peng S, Gao J, Liu W, Jiang C, Yang X, Sun Y, et al. Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation. Oncotarget. 2016;7:80262-80274 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 5a
| Wang L, Cano M, Datta S, Wei H, Ebrahimi K, Gorashi Y, et al. Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation. J Pathol. 2016;240:495-506 pubmed publisher
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- western blot; mouse; fig 3
| Ravindran R, Loebbermann J, Nakaya H, Khan N, Ma H, Gama L, et al. The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature. 2016;531:523-527 pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:300
| Liu R, Wang A, To E, Gao J, Cao S, Cui J, et al. Vinpocetine inhibits amyloid-beta induced activation of NF-?B, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells. Exp Eye Res. 2014;127:49-58 pubmed publisher
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- western blot; human; 1:1000
| Zhen J, Zhang L, Pan J, Ma S, Yu X, Li X, et al. AIM2 mediates inflammation-associated renal damage in hepatitis B virus-associated glomerulonephritis by regulating caspase-1, IL-1?, and IL-18. Mediators Inflamm. 2014;2014:190860 pubmed publisher
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| Ojeda D, Grasso D, Urquiza J, Till A, Vaccaro M, Quarleri J. Cell Death Is Counteracted by Mitophagy in HIV-Productively Infected Astrocytes but Is Promoted by Inflammasome Activation Among Non-productively Infected Cells. Front Immunol. 2018;9:2633 pubmed publisher
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| Zhang J, Lai X, Chen M, Guo Y. Tim-3 exacerbates kidney ischaemia/reperfusion injury through the TLR-4/NF-κB signalling pathway and an NLR-C4 inflammasome activation. Clin Exp Immunol. 2018;193:113-129 pubmed publisher
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| Khalafalla M, Woods L, Camden J, Khan A, Limesand K, Petris M, et al. P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy. J Biol Chem. 2017;292:16626-16637 pubmed publisher
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| Zhao J, Mou Y, Bernstock J, Klimanis D, Wang S, Spatz M, et al. Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats. PLoS ONE. 2015;10:e0140772 pubmed publisher
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