This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Alkaline Phosphatase, Tissue Non-Specific antibody [EPR4477]
catalog :
ab108337
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR4477
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
Yang M, Li C, Xiao Y, Guo Q, Huang Y, Su T, et al. Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation. Cell Prolif. 2020;53:e12784 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1d, 4a
Darrieutort Laffite C, Arnolfo P, Garraud T, Adrait A, Coute Y, Louarn G, et al. Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner. J Clin Med. 2019;8: pubmed publisher
  • western blot; mouse; loading ...; fig 1f
Yang H, Zhang M, Liu Q, Zhang H, Zhang J, Lu L, et al. Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism. Int J Mol Sci. 2019;20: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 9a
Dosh R, Jordan Mahy N, Sammon C, Le Maitre C. Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model. Oncotarget. 2019;10:3559-3575 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Chen X, Chen J, Xu D, Zhao S, Song H, Peng Y. Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs. BMC Musculoskelet Disord. 2017;18:423 pubmed publisher
  • western blot; human; loading ...; fig 2a
Zeng Q, Song R, Fullerton D, Ao L, Zhai Y, Li S, et al. Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc Natl Acad Sci U S A. 2017;114:1631-1636 pubmed publisher
  • flow cytometry; mouse; 10 ug/ml; fig s3
  • flow cytometry; human; fig s3
Li D, Liu J, Guo B, Liang C, Dang L, Lu C, et al. Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation. Nat Commun. 2016;7:10872 pubmed publisher
  • western blot; human; 1:20,000; loading ...; fig 4e
Huang X, Huang S, Guo F, Xu F, Cheng P, Ye Y, et al. Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro. Mol Med Rep. 2016;13:613-22 pubmed publisher
  • western blot; dogs; fig s3a
Neumann Z, Pondenis H, Masyr A, Byrum M, Wycislo K, Fan T. The Association of Endothelin-1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma. J Vet Intern Med. 2015;29:1584-94 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250
  • western blot; mouse; 1:1000
Choi K, Kang B, Kim H, Lee S, Bae S, Kweon O, et al. Low-level laser therapy promotes the osteogenic potential of adipose-derived mesenchymal stem cells seeded on an acellular dermal matrix. J Biomed Mater Res B Appl Biomater. 2013;101:919-28 pubmed publisher
Muscarella A, Dai W, Mitchell P, Zhang W, Wang H, Jia L, et al. Unique cellular protrusions mediate breast cancer cell migration by tethering to osteogenic cells. NPJ Breast Cancer. 2020;6:42 pubmed publisher
Lee E, Nam Y, Kang S, Choi E, Han I, Kim J, et al. The local hypothalamic-pituitary-adrenal axis in cultured human dermal papilla cells. BMC Mol Cell Biol. 2020;21:42 pubmed publisher
Ryu J, Kwon D, Choe N, Shin S, Jeong G, Lim Y, et al. Characterization of Circular RNAs in Vascular Smooth Muscle Cells with Vascular Calcification. Mol Ther Nucleic Acids. 2019;19:31-41 pubmed publisher
Li H, Yue L, Xu H, Li N, Li J, Zhang Z, et al. Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway. Aging (Albany NY). 2019;11:6983-6998 pubmed publisher
Fei D, Zhang Y, Wu J, Zhang H, Liu A, He X, et al. Cav 1.2 regulates osteogenesis of bone marrow-derived mesenchymal stem cells via canonical Wnt pathway in age-related osteoporosis. Aging Cell. 2019;18:e12967 pubmed publisher
Liu W, Zhang L, Xuan K, Hu C, Li L, Zhang Y, et al. Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia. Theranostics. 2018;8:5575-5592 pubmed publisher
Wang H, Tian L, Goldstein A, Liu J, Lo H, Sheng K, et al. Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies. Nat Commun. 2017;8:15045 pubmed publisher
Shen X, Geng Y, Liu P, Huang X, Li S, Liu C, et al. Magnitude-dependent response of osteoblasts regulated by compressive stress. Sci Rep. 2017;7:44925 pubmed publisher
Strauss S, Neumeister A, Barcikowski S, Kracht D, Kuhbier J, Radtke C, et al. Adhesion, vitality and osteogenic differentiation capacity of adipose derived stem cells seeded on nitinol nanoparticle coatings. PLoS ONE. 2013;8:e53309 pubmed publisher
Straus S, Dudziak S, Hagemann R, Barcikowski S, Fliess M, Israelowitz M, et al. Induction of osteogenic differentiation of adipose derived stem cells by microstructured nitinol actuator-mediated mechanical stress. PLoS ONE. 2012;7:e51264 pubmed publisher
product information
CatalogNumber :
ab108337
ItemName :
Anti-Alkaline Phosphatase, Tissue Non-Specific antibody [EPR4477]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR4477
Size :
10 µl, 100 µl
SpeciesSummary :
Hu, Ms, Rat
Application Summary :
Flow Cyt, ICC/IF, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK