This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
FOXP3 antibody
catalog :
ab10563
quantity :
100 ug
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 33
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse
Lopes Pacheco M, Ventura T, de Oliveira H, Monção Ribeiro L, Gutfilen B, de Souza S, et al. Infusion of bone marrow mononuclear cells reduces lung fibrosis but not inflammation in the late stages of murine silicosis. PLoS ONE. 2014;9:e109982 pubmed publisher
Tyagi R, Miles B, Parmar R, Garg N, Dalai S, Baban B, et al. Human IDO-competent, long-lived immunoregulatory dendritic cells induced by intracellular pathogen, and their fate in humanized mice. Sci Rep. 2017;7:41083 pubmed publisher
Wilson A, Hicks C. Both tumour cells and infiltrating T-cells in equine sarcoids express FOXP3 associated with an immune-supressed cytokine microenvironment. Vet Res. 2016;47:55 pubmed publisher
Zhu H, Behr B, Reddy V, Hughes M, Pan Y, Baker J. Human Embryonic Stem Cell Lines with Lesions in FOXP3 and NF1. PLoS ONE. 2016;11:e0151836 pubmed publisher
Scalea J, Torabi R, Tena A, Tasaki M, Gillon B, Moran S, et al. The rejuvenating effects of leuprolide acetate on the aged baboon's thymus. Transpl Immunol. 2014;31:134-9 pubmed publisher
Liu X, Li H, Liu J, Guan Y, Huang L, Tang H, et al. Immune reconstitution from peripheral blood mononuclear cells inhibits lung carcinoma growth in NOD/SCID mice. Oncol Lett. 2014;8:1638-1644 pubmed
Jiang Y, Du Z, Yang F, Di Y, Li J, Zhou Z, et al. FOXP3+ lymphocyte density in pancreatic cancer correlates with lymph node metastasis. PLoS ONE. 2014;9:e106741 pubmed publisher
Tunçel T, Karagoz B, Haholu A, Ozgun A, Emirzeoğlu L, Bilgi O, et al. Immunoregulatory function of HLA-G in gastric cancer. Asian Pac J Cancer Prev. 2013;14:7681-4 pubmed
Tan B, Anaka M, Deb S, Freyer C, Ebert L, Chueh A, et al. FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Oncotarget. 2014;5:264-76 pubmed
Szylberg Ł, Bodnar M, Harasymczuk J, Marszalek A. Expression of FoxP3 protein plays a key role in thyroid tumors in children. Fetal Pediatr Pathol. 2014;33:84-91 pubmed publisher
Dummer C, Carpio V, da Silva Loreto M, Joelsons G, Carraro D, Olivieri E, et al. Analysis of FOXP3 gene and protein expressions in renal allograft biopsies and their association with graft outcomes. Ren Fail. 2013;35:521-30 pubmed publisher
Suzuki H, Onishi H, Morisaki T, Tanaka M, Katano M. Intratumoral FOXP3+VEGFR2+ regulatory T cells are predictive markers for recurrence and survival in patients with colorectal cancer. Clin Immunol. 2013;146:26-33 pubmed publisher
Hsu P, Santner Nanan B, Dahlstrom J, Fadia M, Chandra A, Peek M, et al. Altered decidual DC-SIGN+ antigen-presenting cells and impaired regulatory T-cell induction in preeclampsia. Am J Pathol. 2012;181:2149-60 pubmed publisher
Zeng C, Yao Y, Jie W, Zhang M, Hu X, Zhao Y, et al. Up-regulation of Foxp3 participates in progression of cervical cancer. Cancer Immunol Immunother. 2013;62:481-7 pubmed publisher
Alexandrescu S, Tatevian N, Czerniak B, Covinsky M, Burns N, Brown R. Morphoproteomics provides support for TGF-? pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis. Int J Clin Exp Pathol. 2012;5:503-11 pubmed
von Boehmer L, Draenert A, Jungraithmayr W, Inci I, Niklaus S, Boehler A, et al. Immunosuppression and lung cancer of donor origin after bilateral lung transplantation. Lung Cancer. 2012;76:118-22 pubmed publisher
Chan D, Somani A, Young A, Massari J, Ohtola J, Sugiyama H, et al. Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32). BMC Biochem. 2011;12:27 pubmed publisher
Kofler D, Chmielewski M, Rappl G, Hombach A, Riet T, Schmidt A, et al. CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation. Mol Ther. 2011;19:760-7 pubmed publisher
Loeffler C, Dietz K, Schleich A, Schlaszus H, Stoll M, Meyermann R, et al. Immune surveillance of the normal human CNS takes place in dependence of the locoregional blood-brain barrier configuration and is mainly performed by CD3(+)/CD8(+) lymphocytes. Neuropathology. 2011;31:230-8 pubmed publisher
Chen Y, Nikulina K, Lazarev S, Bahrami A, Noble L, Gallup M, et al. Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjögren's syndrome. Am J Pathol. 2010;177:1333-43 pubmed publisher
Kosmidis M, Dziunycz P, Suárez Fariñas M, Mühleisen B, Schärer L, Lauchli S, et al. Immunosuppression affects CD4+ mRNA expression and induces Th2 dominance in the microenvironment of cutaneous squamous cell carcinoma in organ transplant recipients. J Immunother. 2010;33:538-46 pubmed publisher
Mühleisen B, Petrov I, Gächter T, Kurrer M, Schärer L, Dummer R, et al. Progression of cutaneous squamous cell carcinoma in immunosuppressed patients is associated with reduced CD123+ and FOXP3+ cells in the perineoplastic inflammatory infiltrate. Histopathology. 2009;55:67-76 pubmed publisher
Ashton Chess J, Dugast E, Colvin R, Giral M, Foucher Y, Moreau A, et al. Regulatory, effector, and cytotoxic T cell profiles in long-term kidney transplant patients. J Am Soc Nephrol. 2009;20:1113-22 pubmed publisher
Torchia D, Caproni M, Volpi W, Fabbri P. Naturally occurring regulatory T cells in mucous membrane pemphigoid lesions. Acta Dermatovenerol Alp Pannonica Adriat. 2009;18:3-6 pubmed
Plumb J, Smyth L, Adams H, Vestbo J, Bentley A, Singh S. Increased T-regulatory cells within lymphocyte follicles in moderate COPD. Eur Respir J. 2009;34:89-94 pubmed publisher
Hansenne I, Louis C, Martens H, Dorban G, Charlet Renard C, Peterson P, et al. Aire and Foxp3 expression in a particular microenvironment for T cell differentiation. Neuroimmunomodulation. 2009;16:35-44 pubmed publisher
Graciolli F, Neves K, dos Reis L, Graciolli R, Noronha I, Moyses R, et al. Phosphorus overload and PTH induce aortic expression of Runx2 in experimental uraemia. Nephrol Dial Transplant. 2009;24:1416-21 pubmed publisher
Rappl G, Schmidt A, Mauch C, Hombach A, Abken H. Extensive amplification of human regulatory T cells alters their functional capacities and targets them to the periphery. Rejuvenation Res. 2008;11:915-33 pubmed publisher
Oble D, Mino Kenudson M, Goldsmith J, Hodi F, Seliem R, Dranoff G, et al. Alpha-CTLA-4 mAb-associated panenteritis: a histologic and immunohistochemical analysis. Am J Surg Pathol. 2008;32:1130-7 pubmed publisher
Van Bruaene N, Perez Novo C, Basinski T, Van Zele T, Holtappels G, De Ruyck N, et al. T-cell regulation in chronic paranasal sinus disease. J Allergy Clin Immunol. 2008;121:1435-41, 1441.e1-3 pubmed publisher
Ebert L, Tan B, Browning J, Svobodova S, Russell S, Kirkpatrick N, et al. The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells. Cancer Res. 2008;68:3001-9 pubmed publisher
Ghebeh H, Barhoush E, Tulbah A, Elkum N, Al Tweigeri T, Dermime S. FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. BMC Cancer. 2008;8:57 pubmed publisher
Tzartos J, Friese M, Craner M, Palace J, Newcombe J, Esiri M, et al. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol. 2008;172:146-55 pubmed
product information
Catalog Number :
ab10563
Product Name :
FOXP3 antibody
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Primary antibodies
Size :
100 ug
SwissProtID :
Q9BZS1
Isotype :
IgG
CrossReactivity :
Reacts with: Human. Predicted to react with: Macaque Monkey. Does not react with: Mouse.
Application Summary :
Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK