This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Histone H3 (tri methyl K4) antibody [mAbcam1012] - ChIP Grade
catalog :
ab1012
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAbcam1012
reactivity :
hamsters, Saccharomycetales, human, mouse, rat, bovine, zebrafish , Xenopus laevis, thale cress
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, ChIP-Seq
citations: 109
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 6b
Fujimoto M, Takii R, Katiyar A, Srivastava P, Nakai A. Poly(ADP-Ribose) Polymerase 1 Promotes the Human Heat Shock Response by Facilitating Heat Shock Transcription Factor 1 Binding to DNA. Mol Cell Biol. 2018;38: pubmed publisher
  • ChIP-Seq; mouse; loading ...; fig 5a
Wu H, Gordon J, Whitfield T, Tai P, Van Wijnen A, Stein J, et al. Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis. Biochim Biophys Acta Gene Regul Mech. 2017;1860:438-449 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 5c
Qiu Z, Elsayed Z, Peterkin V, Alkatib S, Bennett D, Landry J. Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression. BMC Biol. 2016;14:18 pubmed publisher
  • chromatin immunoprecipitation; thale cress; fig 3
Liu N, Avramova Z. Molecular mechanism of the priming by jasmonic acid of specific dehydration stress response genes in Arabidopsis. Epigenetics Chromatin. 2016;9:8 pubmed publisher
  • chromatin immunoprecipitation; hamsters; fig 7
Veith N, Ziehr H, MacLeod R, Reamon Buettner S. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines. BMC Biotechnol. 2016;16:6 pubmed publisher
  • chromatin immunoprecipitation; Xenopus laevis; fig s2
Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, et al. Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis. Cell Biosci. 2016;6:2 pubmed publisher
  • ChIP-Seq; human; fig 2
  • immunocytochemistry; human; fig s2
Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
  • western blot; human; fig s3
Peng D, Kryczek I, Nagarsheth N, Zhao L, Wei S, Wang W, et al. Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy. Nature. 2015;527:249-53 pubmed publisher
  • western blot; human; fig s2
Lu S, Yang Y, Du Y, Cao L, Li M, Shen C, et al. The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. Oncotarget. 2015;6:34704-17 pubmed publisher
  • western blot; human
Gunes A, Iscan E, Topel H, Avci S, Gumustekin M, Erdal E, et al. Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells. Int J Biochem Cell Biol. 2015;65:169-81 pubmed publisher
  • chromatin immunoprecipitation; mouse; loading ...; fig 1
Takahashi J, Kumar V, Nakashe P, Koike N, Huang H, Green C, et al. ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals. Methods Enzymol. 2015;551:285-321 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 1, 2
  • western blot; mouse; fig 5
Wijeweera A, Haj M, Feldman A, Pnueli L, Luo Z, Melamed P. Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin. Biochim Biophys Acta. 2015;1849:328-41 pubmed publisher
  • chromatin immunoprecipitation; zebrafish
de Oliveira S, Boudinot P, Calado Ã, Mulero V. Duox1-derived H2O2 modulates Cxcl8 expression and neutrophil recruitment via JNK/c-JUN/AP-1 signaling and chromatin modifications. J Immunol. 2015;194:1523-33 pubmed publisher
  • chromatin immunoprecipitation; human; fig 6
Karamitros D, Patmanidi A, Kotantaki P, Potocnik A, Bähr Ivacevic T, Benes V, et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 2015;142:70-81 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 2
Naik A, Hawwari A, Krangel M. Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters. J Immunol. 2015;194:790-4 pubmed publisher
  • chromatin immunoprecipitation; human
Suzuki A, Makinoshima H, Wakaguri H, Esumi H, Sugano S, Kohno T, et al. Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines. Nucleic Acids Res. 2014;42:13557-72 pubmed publisher
  • immunocytochemistry; human; 1:25
Bakhtari A, Rahmani H, Bonakdar E, Jafarpour F, Asgari V, Hosseini S, et al. The interfering effects of superovulation and vitrification upon some important epigenetic biomarkers in mouse blastocyst. Cryobiology. 2014;69:419-27 pubmed publisher
  • ChIP-Seq; human; fig 1
  • chromatin immunoprecipitation; human; fig s3
Herranz D, Ambesi Impiombato A, Palomero T, Schnell S, Belver L, Wendorff A, et al. A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nat Med. 2014;20:1130-7 pubmed publisher
  • ChIP-Seq; human
Matsumoto K, Suzuki A, Wakaguri H, Sugano S, Suzuki Y. Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites. Nucleic Acids Res. 2014;42:e125 pubmed publisher
  • western blot; human
Mungamuri S, Wang S, Manfredi J, Gu W, Aaronson S. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene. 2015;34:2461-70 pubmed publisher
  • chromatin immunoprecipitation; mouse
Tai P, Wu H, Gordon J, Whitfield T, Barutcu A, Van Wijnen A, et al. Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region. Gene. 2014;550:1-9 pubmed publisher
  • chromatin immunoprecipitation; mouse
Seki M, Masaki H, Arauchi T, Nakauchi H, Sugano S, Suzuki Y. A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells. PLoS ONE. 2014;9:e95374 pubmed publisher
  • chromatin immunoprecipitation; Saccharomycetales
  • western blot; Saccharomycetales
Maltby V, Martin B, Brind Amour J, Chruscicki A, McBurney K, Schulze J, et al. Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2012;109:18505-10 pubmed publisher
  • chromatin immunoprecipitation; mouse
Makeyev A, Enkhmandakh B, Hong S, Joshi P, Shin D, Bayarsaihan D. Diversity and complexity in chromatin recognition by TFII-I transcription factors in pluripotent embryonic stem cells and embryonic tissues. PLoS ONE. 2012;7:e44443 pubmed publisher
Meng S, Shi H, Lin C, Wu Z, Lin F, Tao Z, et al. UvKmt2-Mediated H3K4 Trimethylation Is Required for Pathogenicity and Stress Response in Ustilaginoidea virens. J Fungi (Basel). 2022;8: pubmed publisher
Lemster A, Sievers E, Pasternack H, Lazar Karsten P, Klümper N, Sailer V, et al. Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMT. Cancers (Basel). 2022;14: pubmed publisher
Meng S, Liu Z, Shi H, Wu Z, Qiu J, Wen H, et al. UvKmt6-mediated H3K27 trimethylation is required for development, pathogenicity, and stress response in Ustilaginoidea virens. Virulence. 2021;12:2972-2988 pubmed publisher
Du M, Gong P, Zhang Y, Liu Y, Liu X, Zhang F, et al. Histone methyltransferase SETD1A participates in lung cancer progression. Thorac Cancer. 2021;12:2247-2257 pubmed publisher
Ghasemi R, Struthers H, Wilson E, Spencer D. Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells. Leukemia. 2021;35:404-416 pubmed publisher
Liu N, Yin Y, Wang H, Zhou Z, Sheng X, Fu H, et al. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling. PLoS Genet. 2019;15:e1008368 pubmed publisher
Wang S, Zhang C, Hasson D, Desai A, SenBanerjee S, Magnani E, et al. Epigenetic Compensation Promotes Liver Regeneration. Dev Cell. 2019;: pubmed publisher
Vandenbon A, Kumagai Y, Lin M, Suzuki Y, Nakai K. Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation. Genome Biol. 2018;19:138 pubmed publisher
Strub T, Ghiraldini F, Carcamo S, Li M, Wroblewska A, Singh R, et al. SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling. Nat Commun. 2018;9:3440 pubmed publisher
Truong D, Boeke J. Resetting the Yeast Epigenome with Human Nucleosomes. Cell. 2017;171:1508-1519.e13 pubmed publisher
Duteil D, Tosic M, Willmann D, Georgiadi A, Kanouni T, Schüle R. Lsd1 prevents age-programed loss of beige adipocytes. Proc Natl Acad Sci U S A. 2017;114:5265-5270 pubmed publisher
Liu K, Mao J, Song L, Fan A, Zhang S, Wang J, et al. DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells. PLoS ONE. 2017;12:e0173047 pubmed publisher
Martin B, McBurney K, Maltby V, Jensen K, Brind Amour J, Howe L. Histone H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone Acetyltransferase in Saccharomyces cerevisiae. Genetics. 2017;205:1113-1123 pubmed publisher
Mendoza Parra M, Saravaki V, Cholley P, Blum M, Billoré B, Gronemeyer H. Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification. F1000Res. 2016;5:54 pubmed publisher
Vaidya H, Rumph C, Katula K. Inactivation of the WNT5A Alternative Promoter B Is Associated with DNA Methylation and Histone Modification in Osteosarcoma Cell Lines U2OS and SaOS-2. PLoS ONE. 2016;11:e0151392 pubmed publisher
Messier T, Gordon J, Boyd J, Tye C, Browne G, Stein J, et al. Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes. Oncotarget. 2016;7:5094-109 pubmed publisher
Bansal N, Petrie K, Christova R, Chung C, Leibovitch B, Howell L, et al. Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer. Oncotarget. 2015;6:34087-105 pubmed publisher
Singh A, Sun Y, Li L, Zhang W, Wu T, Zhao S, et al. Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency. Stem Cell Reports. 2015;5:323-36 pubmed publisher
Trombly D, Whitfield T, Padmanabhan S, Gordon J, Lian J, Van Wijnen A, et al. Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells. BMC Genomics. 2015;16:309 pubmed publisher
Maekawa S, Imamachi N, Irie T, Tani H, Matsumoto K, Mizutani R, et al. Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance. BMC Genomics. 2015;16:154 pubmed publisher
Sosa M, Parikh F, Maia A, Estrada Y, Bosch A, Bragado P, et al. NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes. Nat Commun. 2015;6:6170 pubmed publisher
Müller Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, et al. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res. 2015;43:1577-92 pubmed publisher
Duarte L, Young A, Wang Z, Wu H, Panda T, Kou Y, et al. Histone H3.3 and its proteolytically processed form drive a cellular senescence programme. Nat Commun. 2014;5:5210 pubmed publisher
Papazyan R, Voronina E, Chapman J, Luperchio T, Gilbert T, Meier E, et al. Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. elife. 2014;3:e02996 pubmed publisher
Meyer M, Benkusky N, Lee C, Pike J. Genomic determinants of gene regulation by 1,25-dihydroxyvitamin D3 during osteoblast-lineage cell differentiation. J Biol Chem. 2014;289:19539-54 pubmed publisher
St John H, Bishop K, Meyer M, Benkusky N, Leng N, Kendziorski C, et al. The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone. Mol Endocrinol. 2014;28:1150-65 pubmed publisher
Kolodziej S, Kuvardina O, Oellerich T, Herglotz J, Backert I, Kohrs N, et al. PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation. Nat Commun. 2014;5:3995 pubmed publisher
Yang X, Hegde V, Rao R, Zhang J, Nagarkatti P, Nagarkatti M. Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses. J Biol Chem. 2014;289:18707-18 pubmed publisher
Meyer M, Benkusky N, Pike J. The RUNX2 cistrome in osteoblasts: characterization, down-regulation following differentiation, and relationship to gene expression. J Biol Chem. 2014;289:16016-31 pubmed publisher
Liu N, Ding Y, Fromm M, Avramova Z. Different gene-specific mechanisms determine the 'revised-response' memory transcription patterns of a subset of A. thaliana dehydration stress responding genes. Nucleic Acids Res. 2014;42:5556-66 pubmed publisher
Goeman F, De Nicola F, D Onorio De Meo P, Pallocca M, Elmi B, Castrignanò T, et al. VDR primary targets by genome-wide transcriptional profiling. J Steroid Biochem Mol Biol. 2014;143:348-56 pubmed publisher
Hackermüller J, Reiche K, Otto C, Hösler N, Blumert C, Brocke Heidrich K, et al. Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. Genome Biol. 2014;15:R48 pubmed publisher
Hauser J, Grundström C, Grundström T. Allelic exclusion of IgH through inhibition of E2A in a VDJ recombination complex. J Immunol. 2014;192:2460-70 pubmed publisher
Min H, Lee J, Kim M. Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9:960-5 pubmed publisher
Wang T, Nandakumar V, Jiang X, Jones L, Yang A, Huang X, et al. The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood. 2013;122:2812-22 pubmed publisher
Nosaka M, Ono A, Ishiwata A, Shimizu Sato S, Ishimoto K, Noda Y, et al. Expression of the rice microRNA miR820 is associated with epigenetic modifications at its own locus. Genes Genet Syst. 2013;88:105-12 pubmed
Schnerch A, Rampalii S, Bhatia M. Histone modification profiling in normal and transformed human embryonic stem cells using micro chromatin immunoprecipitation, scalable to genome-wide microarray analyses. Methods Mol Biol. 2013;1029:149-61 pubmed publisher
Pang B, Qiao X, Janssen L, Velds A, Groothuis T, Kerkhoven R, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908 pubmed publisher
Vo T, Revesz A, Sohi G, Ma N, Hardy D. Maternal protein restriction leads to enhanced hepatic gluconeogenic gene expression in adult male rat offspring due to impaired expression of the liver X receptor. J Endocrinol. 2013;218:85-97 pubmed publisher
Xiong Z, LaDana C, Wu D, Cao K. An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells. Aging (Albany NY). 2013;5:288-303 pubmed
Light W, Freaney J, Sood V, Thompson A, D Urso A, Horvath C, et al. A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. PLoS Biol. 2013;11:e1001524 pubmed publisher
Bevington S, Boyes J. Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination. EMBO J. 2013;32:1381-92 pubmed publisher
Deplus R, Delatte B, Schwinn M, Defrance M, Méndez J, Murphy N, et al. TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J. 2013;32:645-55 pubmed publisher
Moison C, Senamaud Beaufort C, Fourrière L, Champion C, Ceccaldi A, Lacomme S, et al. DNA methylation associated with polycomb repression in retinoic acid receptor ? silencing. FASEB J. 2013;27:1468-78 pubmed publisher
Zuo B, Yang J, Wang F, Wang L, Yin Y, Dan J, et al. Influences of lamin A levels on induction of pluripotent stem cells. Biol Open. 2012;1:1118-27 pubmed publisher
Goula A, Styś A, Chan J, Trottier Y, Festenstein R, Merienne K. Transcription elongation and tissue-specific somatic CAG instability. PLoS Genet. 2012;8:e1003051 pubmed publisher
Boedi S, Reyes Dominguez Y, Strauss J. Chromatin immunoprecipitation analysis in filamentous fungi. Methods Mol Biol. 2012;944:221-36 pubmed publisher
Shpargel K, Sengoku T, Yokoyama S, Magnuson T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012;8:e1002964 pubmed publisher
Bernardino L, Eiriz M, Santos T, Xapelli S, Grade S, Rosa A, et al. Histamine stimulates neurogenesis in the rodent subventricular zone. Stem Cells. 2012;30:773-84 pubmed publisher
Medina R, Ghule P, Cruzat F, Barutcu A, Montecino M, Stein J, et al. Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. Mol Cell Biol. 2012;32:3860-71 pubmed publisher
Janzer A, Stamm K, Becker A, Zimmer A, Buettner R, Kirfel J. The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts. J Biol Chem. 2012;287:30984-92 pubmed publisher
Rodríguez Esparragón F, Serna Gómez J, Hernández Velázquez E, Buset Ríos N, Hernández Trujillo Y, Garcia Bello M, et al. Homocysteinylated protein levels in internal mammary artery (IMA) fragments and its genotype-dependence. S-homocysteine-induced methylation modifications in IMA and aortic fragments. Mol Cell Biochem. 2012;369:235-46 pubmed publisher
Maltby V, Martin B, Schulze J, Johnson I, Hentrich T, Sharma A, et al. Histone H3 lysine 36 methylation targets the Isw1b remodeling complex to chromatin. Mol Cell Biol. 2012;32:3479-85 pubmed publisher
Reamon Buettner S, Borlak J. Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene Cadm1. PLoS ONE. 2012;7:e38531 pubmed publisher
Nohara K, Tateishi Y, Suzuki T, Okamura K, Murai H, Takumi S, et al. Late-onset increases in oxidative stress and other tumorigenic activities and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic. Toxicol Sci. 2012;129:293-304 pubmed publisher
Tyan S, Hsu C, Peng K, Chen C, Kuo W, Lee E, et al. Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change. PLoS ONE. 2012;7:e35128 pubmed publisher
Peach S, Rudomin E, Udeshi N, Carr S, Jaffe J. Quantitative assessment of chromatin immunoprecipitation grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules. Mol Cell Proteomics. 2012;11:128-37 pubmed publisher
Youn M, Yokoyama A, Fujiyama Nakamura S, Ohtake F, Minehata K, Yasuda H, et al. JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation. J Biol Chem. 2012;287:12994-3004 pubmed publisher
Nijwening J, Geutjes E, Bernards R, Beijersbergen R. The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence. PLoS ONE. 2011;6:e25235 pubmed publisher
Emanuele M, Costa S, Ragusa M, Gianguzza F. Chromatin dynamics of the developmentally regulated P. lividus neural alpha tubulin gene. Int J Dev Biol. 2011;55:591-6 pubmed publisher
Nakamura T, Nakagawa M, Ichisaka T, Shiota A, Yamanaka S. Essential roles of ECAT15-2/Dppa2 in functional lung development. Mol Cell Biol. 2011;31:4366-78 pubmed publisher
Li W, Liu H, Cheng Z, Su Y, Han H, Zhang Y, et al. DNA methylation and histone modifications regulate de novo shoot regeneration in Arabidopsis by modulating WUSCHEL expression and auxin signaling. PLoS Genet. 2011;7:e1002243 pubmed publisher
Wakabayashi Y, Tamiya T, Takada I, Fukaya T, Sugiyama Y, Inoue N, et al. Histone 3 lysine 9 (H3K9) methyltransferase recruitment to the interleukin-2 (IL-2) promoter is a mechanism of suppression of IL-2 transcription by the transforming growth factor-?-Smad pathway. J Biol Chem. 2011;286:35456-65 pubmed publisher
Sacilotto N, Espert A, Castillo J, Franco L, López Rodas G. Epigenetic transcriptional regulation of the growth arrest-specific gene 1 (Gas1) in hepatic cell proliferation at mononucleosomal resolution. PLoS ONE. 2011;6:e23318 pubmed publisher
Kanai A, Suzuki K, Tanimoto K, Mizushima Sugano J, Suzuki Y, Sugano S. Characterization of STAT6 target genes in human B cells and lung epithelial cells. DNA Res. 2011;18:379-92 pubmed publisher
Watanabe K, Emoto N, Hamano E, Sunohara M, Kawakami M, Kage H, et al. Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer. Int J Cancer. 2012;130:2580-90 pubmed publisher
Liu X, Wang J, Li R, Yang X, Sun Q, Albrecht E, et al. Maternal dietary protein affects transcriptional regulation of myostatin gene distinctively at weaning and finishing stages in skeletal muscle of Meishan pigs. Epigenetics. 2011;6:899-907 pubmed
Yamasaki S, Oda M, Daimon H, Mitsukuri K, Johkan M, Nakatsuka T, et al. Epigenetic modifications of the 35S promoter in cultured gentian cells. Plant Sci. 2011;180:612-9 pubmed publisher
Yamashita R, Sathira N, Kanai A, Tanimoto K, Arauchi T, Tanaka Y, et al. Genome-wide characterization of transcriptional start sites in humans by integrative transcriptome analysis. Genome Res. 2011;21:775-89 pubmed publisher
Stratmann A, Haendler B. The histone demethylase JARID1A regulates progesterone receptor expression. FEBS J. 2011;278:1458-69 pubmed publisher
Vargova K, Curik N, Burda P, Basova P, Kulvait V, Pospisil V, et al. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. Blood. 2011;117:3816-25 pubmed publisher
Fuchs S, Krajewski K, Baker R, Miller V, Strahl B. Influence of combinatorial histone modifications on antibody and effector protein recognition. Curr Biol. 2011;21:53-8 pubmed publisher
Chakravarthy H, Ormsbee B, Mallanna S, Rizzino A. Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery. FASEB J. 2011;25:206-18 pubmed publisher
LaPlant Q, Vialou V, Covington H, Dumitriu D, Feng J, Warren B, et al. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci. 2010;13:1137-43 pubmed publisher
Sanders Y, Tollefsbol T, Varisco B, Hagood J. Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. Am J Respir Cell Mol Biol. 2011;45:16-23 pubmed publisher
Shahhoseini M, Taei A, Mehrjardi N, Salekdeh G, Baharvand H. Epigenetic analysis of human embryonic carcinoma cells during retinoic acid-induced neural differentiation. Biochem Cell Biol. 2010;88:527-38 pubmed publisher
Philipot O, Joliot V, Ait Mohamed O, Pellentz C, Robin P, Fritsch L, et al. The core binding factor CBF negatively regulates skeletal muscle terminal differentiation. PLoS ONE. 2010;5:e9425 pubmed publisher
Venkatarama T, Lai F, Luo X, Zhou Y, Newman K, King M. Repression of zygotic gene expression in the Xenopus germline. Development. 2010;137:651-60 pubmed publisher
Anelli V, Santoriello C, Distel M, Köster R, Ciccarelli F, Mione M. Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation. Zebrafish. 2009;6:417-24 pubmed publisher
Kusakabe M, Watanabe K, Emoto N, Aki N, Kage H, Nagase T, et al. Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. Biochem Biophys Res Commun. 2009;390:1283-7 pubmed publisher
Takahashi A, Obata Y, Fukumoto Y, Nakayama Y, Kasahara K, Kuga T, et al. Nuclear localization of Src-family tyrosine kinases is required for growth factor-induced euchromatinization. Exp Cell Res. 2009;315:1117-41 pubmed publisher
Kim J, Ebersole T, Kouprina N, Noskov V, Ohzeki J, Masumoto H, et al. Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res. 2009;19:533-44 pubmed publisher
Pan Q, Wu Y, Lin T, Yao H, Yang Z, Gao G, et al. Bone morphogenetic protein-2 induces chromatin remodeling and modification at the proximal promoter of Sox9 gene. Biochem Biophys Res Commun. 2009;379:356-61 pubmed publisher
Noer A, Lindeman L, Collas P. Histone H3 modifications associated with differentiation and long-term culture of mesenchymal adipose stem cells. Stem Cells Dev. 2009;18:725-36 pubmed publisher
Masaki H, Nishida T, Kitajima S, Asahina K, Teraoka H. Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage. J Biol Chem. 2007;282:33034-42 pubmed
product information
Catalog Number :
ab1012
Product Name :
Histone H3 (tri methyl K4) antibody [mAbcam1012] - ChIP Grade
Host Species :
Mouse
Clonality :
monoclonal
AntigenModification :
Tri methyl
Product Type :
Primary antibodies
Size :
100 ug
SwissProtID :
Q93081
Isotype :
IgG2b
CrossReactivity :
Reacts with: Human, Mouse, Rat, Cow, Rice, Zebrafish. Predicted to react with: all Mammals, Arabidopsis thaliana, Caenorhabditis elegans, Fruit fly (Drosophila melanogaster), Schizosaccharomyces pombe, Sheep, Xenopus laevis.
Application Summary :
ChIP, Flow Cyt, ICC, ICC/IF, IHC-Fr, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK