This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Ku80 antibody [EPR3468]
catalog :
Ab80592
quantity :
100µL, 1 mL
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR3468
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:200; loading ...; fig 7
Cao L, Xu C, Yi P, Li H, Lin Y, Cai G, et al. Asparaginyl endopeptidase (AEP) regulates myocardial apoptosis in response to radiation exposure via alterations in NRF2 activation. Am J Cancer Res. 2021;11:1206-1225 pubmed
  • immunocytochemistry; human; loading ...; fig s5
Krzeptowski W, Chudy P, Sokołowski G, Zukowska M, Kusienicka A, Seretny A, et al. Proximity Ligation Assay Detection of Protein-DNA Interactions-Is There a Link between Heme Oxygenase-1 and G-quadruplexes?. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 4e
Yap L, Wang J, Moreno Moral A, Chong L, Sun Y, Harmston N, et al. In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. Cell Rep. 2019;26:3231-3245.e9 pubmed publisher
  • western blot; human; fig 1
Gilmore J, Sardiu M, Groppe B, Thornton J, Liu X, Dayebgadoh G, et al. WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE. 2016;11:e0155492 pubmed publisher
  • western blot; human; 1:10,000; loading ...; fig 3a
Grundy G, Rulten S, Arribas Bosacoma R, Davidson K, Kozik Z, Oliver A, et al. The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins. Nat Commun. 2016;7:11242 pubmed publisher
  • immunohistochemistry; human; 1:500; loading ...; fig 2
Wang S, Wang Z, Yang Y, Shi M, Sun Z. Overexpression of Ku80 correlates with aggressive clinicopathological features and adverse prognosis in esophageal squamous cell carcinoma. Oncol Lett. 2015;10:2705-2712 pubmed
  • western blot; human
Grundy G, Rulten S, Zeng Z, Arribas Bosacoma R, Iles N, Manley K, et al. APLF promotes the assembly and activity of non-homologous end joining protein complexes. EMBO J. 2013;32:112-25 pubmed publisher
Tiwari A, Addis Jones O, Chan K. 53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process. Nat Commun. 2018;9:677 pubmed publisher
Wong R, Lim S, Hung S, Jackson S, Khan S, Van Bergen N, et al. Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy. Aging (Albany NY). 2017;9:1341-1350 pubmed publisher
product information
Catalog Number :
ab80592
Product Name :
Anti-Ku80 antibody [EPR3468]
Product Type :
Primary Antibody
Swiss-Prot ID :
P13010
Host Species :
Rabbit
Clonality :
Monoclonal
Size :
100µL, 1 mL
Application Summary :
Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB
Isotype :
IgG
Reactivity :
Human, Mouse, Rat
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK