This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Androgen Receptor antibody - ChIP Grade
catalog :
Ab74272
quantity :
1 ml
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 4c
Leach D, Mohr A, Giotis E, Cil E, Isac A, Yates L, et al. The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells. Nat Commun. 2021;12:4068 pubmed publisher
  • chromatin immunoprecipitation; human; ; loading ...; fig 1j
Munkley J, Li L, Krishnan S, Hysenaj G, Scott E, Dalgliesh C, et al. Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig S3a
Xue M, Liu H, Zhang L, Chang H, Liu Y, Du S, et al. Computational identification of mutually exclusive transcriptional drivers dysregulating metastatic microRNAs in prostate cancer. Nat Commun. 2017;8:14917 pubmed publisher
  • chromatin immunoprecipitation; rat; loading ...; tbl 1
Kumar A, Dumasia K, Deshpande S, Balasinor N. Direct regulation of genes involved in sperm release by estrogen and androgen through their receptors and coregulators. J Steroid Biochem Mol Biol. 2017;171:66-74 pubmed publisher
  • immunocytochemistry; mouse; fig 4
Zhu M, Bakhru P, Conley B, Nelson J, Free M, Martin A, et al. Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator. Nat Commun. 2016;7:11350 pubmed publisher
Guo J, Wei Z, Jia T, Wang L, Nama N, Liang J, et al. Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions. J Transl Med. 2023;21:716 pubmed publisher
McDermott A, Kim K, Kasper S, Ho S, Leung Y. The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells. Oncotarget. 2022;13:46-60 pubmed publisher
Guo H, Wu Y, Nouri M, Spisak S, Russo J, Sowalsky A, et al. Androgen receptor and MYC equilibration centralizes on developmental super-enhancer. Nat Commun. 2021;12:7308 pubmed publisher
Lee D, Olson A, Wang J, Kim W, Mi J, Zeng H, et al. Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021;148: pubmed publisher
Yuan F, Hankey W, Wu D, Wang H, Somarelli J, Armstrong A, et al. Molecular determinants for enzalutamide-induced transcription in prostate cancer. Nucleic Acids Res. 2019;47:10104-10114 pubmed publisher
Kounatidou E, Nakjang S, McCracken S, Dehm S, Robson C, Jones D, et al. A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. Nucleic Acids Res. 2019;47:5634-5647 pubmed publisher
Deng Q, Zhang J, Wang Z, Zhang S, Zhi F, Liang H. Vesicle-Associated Membrane Protein-Associated Protein A Is Involved in Androgen Receptor Trafficking in Mouse Sertoli Cells. Int J Endocrinol. 2018;2018:4537214 pubmed publisher
Mishra J, More A, Kumar S. Elevated androgen levels induce hyperinsulinemia through increase in Ins1 transcription in pancreatic beta cells in female rats. Biol Reprod. 2018;98:520-531 pubmed publisher
Kreisman M, Song C, Yip K, Natale B, Natale D, Breen K. Androgens Mediate Sex-Dependent Gonadotropin Expression During Late Prenatal Development in the Mouse. Endocrinology. 2017;158:2884-2894 pubmed publisher
Liu Y, Du S, Ding M, Dou X, Zhang F, Wu Z, et al. The BMP4-Smad signaling pathway regulates hyperandrogenism development in a female mouse model. J Biol Chem. 2017;292:11740-11750 pubmed publisher
Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, et al. The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth. J Biol Chem. 2016;291:25983-25998 pubmed
Grabowska M, Kelly S, Reese A, Cates J, Case T, Zhang J, et al. Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016;157:1094-109 pubmed publisher
product information
CatalogNumber :
ab74272
ItemName :
Anti-Androgen Receptor antibody - ChIP Grade
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
1 ml
SpeciesSummary :
Hu, Ms, Rat
Uses :
ChIP, ICC/IF, IHC-Fr, IHC-P, IP, WB
Size Note :
Other sizes available: 10 ml,100 µg,100 µl,500 µl
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK