This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-FOXA1 antibody
catalog :
Ab5089
quantity :
100µg
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, chromatin immunoprecipitation
citations: 15
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; loading ...; fig 2b
De Cecco M, Ito T, Petrashen A, Elias A, Skvir N, Criscione S, et al. L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature. 2019;566:73-78 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 4a
Shukla S, Cyrta J, Murphy D, Walczak E, Ran L, Agrawal P, et al. Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer Cell. 2017;32:792-806.e7 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig s1d
  • western blot; human; loading ...; fig s4b
Toska E, Osmanbeyoglu H, Castel P, Chan C, Hendrickson R, Elkabets M, et al. PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D. Science. 2017;355:1324-1330 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3k
Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed publisher
  • chromatin immunoprecipitation; human; fig 1
Miano V, Ferrero G, Reineri S, Caizzi L, Annaratone L, Ricci L, et al. Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer. Oncotarget. 2016;7:3201-16 pubmed publisher
Qiu H, Makarov V, Bolzenius J, Halstead A, Parker Y, Wang A, et al. KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer. Cancer Res. 2023;83:814-829 pubmed publisher
Geusz R, Wang A, Lam D, Vinckier N, Alysandratos K, Roberts D, et al. Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors. Nat Commun. 2021;12:6636 pubmed publisher
Li Y, Jaiswal S, Kaur R, Alsaadi D, Liang X, Drews F, et al. Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer. BMC Cancer. 2021;21:768 pubmed publisher
Geusz R, Wang A, Chiou J, Lancman J, Wetton N, Kefalopoulou S, et al. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. elife. 2021;10: pubmed publisher
Mazrooei P, Kron K, Zhu Y, Zhou S, Grillo G, Mehdi T, et al. Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors. Cancer Cell. 2019;36:674-689.e6 pubmed publisher
Korkmaz G, Manber Z, Lopes R, Prekovic S, Schuurman K, Kim Y, et al. A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation. Nucleic Acids Res. 2019;47:9557-9572 pubmed publisher
Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, et al. A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer. Mol Cell. 2019;75:791-806.e8 pubmed publisher
Toska E, Castel P, Chhangawala S, Arruabarrena Aristorena A, Chan C, Hristidis V, et al. PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. Cell Rep. 2019;27:294-306.e5 pubmed publisher
Cato L, De Tribolet Hardy J, Lee I, Rottenberg J, Coleman I, Melchers D, et al. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer. Cancer Cell. 2019;35:401-413.e6 pubmed publisher
McMullin R, Dobi A, Mutton L, Orosz A, Maheshwari S, Shashikant C, et al. A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland. Proc Natl Acad Sci U S A. 2010;107:98-103 pubmed publisher
product information
Catalog Number :
ab5089
Product Name :
Anti-FOXA1 antibody
Product Type :
Primary Antibody
Swiss-Prot ID :
P55317
Host Species :
Goat
Clonality :
Polyclonal
Size :
100µg
Application Summary :
ICC, WB
Isotype :
IgG
Reactivity :
Human, Mouse
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK