| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 4e
| Basse A, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, et al. Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. Mol Metab. 2021;53:101271 pubmed publisher |
- western blot; human; loading ...; fig 2g
| Colpitts C, Ridewood S, Schneiderman B, Warne J, Tabata K, Ng C, et al. Hepatitis C virus exploits cyclophilin A to evade PKR. elife. 2020;9: pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 6d
- immunohistochemistry; mouse; 1:500; loading ...; fig 1c
- western blot; mouse; 1:1000; loading ...; fig 1a
| Zhang Y, Lu P, Liang F, Liufu N, Dong Y, ZHENG J, et al. Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain. Front Cell Dev Biol. 2019;7:396 pubmed publisher |
- immunoprecipitation; rat; loading ...; fig 5c
- immunocytochemistry; rat; 1:200; loading ...; fig 5a
- western blot; rat; 1:2000; loading ...; fig 4d
| Xu T, Ding W, Ao X, Chu X, Wan Q, Wang Y, et al. ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening. Redox Biol. 2019;20:414-426 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; mouse; 1:5000; loading ...; fig s2k
| Luongo T, Lambert J, Gross P, Nwokedi M, Lombardi A, Shanmughapriya S, et al. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017;545:93-97 pubmed publisher |
- western blot; human; 1:5000; loading ...; fig 2a
| Senturk S, Shirole N, Nowak D, Corbo V, Pal D, Vaughan A, et al. Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun. 2017;8:14370 pubmed publisher |
- western blot; mouse; loading ...; fig 6g
| Kennedy T, Swiderski K, Murphy K, Gehrig S, Curl C, Chandramouli C, et al. BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle. Am J Pathol. 2016;186:3246-3260 pubmed publisher |
- immunohistochemistry - free floating section; mouse; loading ...; fig 3c
- western blot; mouse; loading ...; fig 3a
| Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed |
- western blot; pigs ; 1:1000; fig 7c
| Hiemstra J, Lee D, Chakir K, Gutiérrez Aguilar M, Marshall K, Zgoda P, et al. Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic-Banded Mini-Swine. J Am Heart Assoc. 2016;5:e003277 pubmed publisher |
- western blot; mouse; 1:500; fig s6
| Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher |
| Gineste C, Hernandez A, Ivarsson N, Cheng A, Naess K, Wibom R, et al. Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy. Hum Mol Genet. 2015;24:6580-7 pubmed publisher |
| Zhang Z, Wang Y, Yan S, Du F, Yan S. NR2B-dependent cyclophilin D translocation suppresses the recovery of synaptic transmission after oxygen-glucose deprivation. Biochim Biophys Acta. 2015;1852:2225-2234 pubmed publisher |
- immunoprecipitation; human; fig 6
- immunocytochemistry; human; fig 5
- western blot; human; fig 5
| Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh A, et al. p53? is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A. 2014;111:E3287-96 pubmed publisher |
- western blot; human; 1:5000
| Fiesel F, Moussaud Lamodière E, Ando M, Springer W. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci. 2014;127:3488-504 pubmed publisher |
- western blot; human; 1:500
| Gouspillou G, Sgarioto N, Kapchinsky S, Purves Smith F, Norris B, Pion C, et al. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 2014;28:1621-33 pubmed publisher |
| Pekson R, Liang F, Axelrod J, Lee J, Qin D, Wittig A, et al. The mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A. 2023;120:e2303713120 pubmed publisher |
| Acosta J, Li Q, Freeburg N, Murali N, Indeglia A, Grothusen G, et al. p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism. Nat Commun. 2023;14:4403 pubmed publisher |
| Mauri S, Bernardo G, Martinez A, Favaro M, Trevisan M, Cobraiville G, et al. USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons. Cells. 2023;12: pubmed publisher |
| Preston A, Rogers A, Sharp M, Mitchell G, Toruno C, Barney B, et al. Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria. Cell Death Discov. 2023;9:66 pubmed publisher |
| Li A, Li X, Yi J, Ma J, Zhou J. Butyrate Feeding Reverses CypD-Related Mitoflash Phenotypes in Mouse Myofibers. Int J Mol Sci. 2021;22: pubmed publisher |
| Pittis A, Goh V, Cebrian Serrano A, Wettmarshausen J, Perocchi F, Gabaldón T. Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter. Nat Commun. 2020;11:4031 pubmed publisher |
| Shivram H, Le S, Iyer V. MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network. Genome Res. 2019;29:184-192 pubmed publisher |
| Wettmarshausen J, Goh V, Huang K, Arduino D, Tripathi U, Leimpek A, et al. MICU1 Confers Protection from MCU-Dependent Manganese Toxicity. Cell Rep. 2018;25:1425-1435.e7 pubmed publisher |
| Parks R, Menazza S, Holmström K, Amanakis G, Fergusson M, Ma H, et al. Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter. Cardiovasc Res. 2019;115:385-394 pubmed publisher |
| Zeng J, Chen B, Lv X, Sun L, Zeng X, Zheng H, et al. Transmembrane member 16A participates in hydrogen peroxide-induced apoptosis by facilitating mitochondria-dependent pathway in vascular smooth muscle cells. Br J Pharmacol. 2018;175:3669-3684 pubmed publisher |
| Debernardi J, Hollville E, Lipinski M, Wiels J, Robert A. Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt's lymphoma cells. Oncogene. 2018;37:2410-2421 pubmed publisher |
| Karam C, Yi J, Xiao Y, Dhakal K, Zhang L, Li X, et al. Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation. Skelet Muscle. 2017;7:6 pubmed publisher |
| Laker R, Taddeo E, Akhtar Y, Zhang M, Hoehn K, Yan Z. The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis. PLoS ONE. 2016;11:e0167910 pubmed publisher |
| Vial G, Le Guen M, Lamarche F, Detaille D, Cottet Rousselle C, Demaison L, et al. Liver mitochondrial function in ZDF rats during the early stages of diabetes disease. Physiol Rep. 2016;4: pubmed publisher |
| Ilgen P, Stoldt S, Conradi L, Wurm C, Ruschoff J, Ghadimi B, et al. STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue. PLoS ONE. 2014;9:e101563 pubmed publisher |
| Qiu F, Chen Y, Liu X, Chu C, Shen L, Xu J, et al. Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells. Sci Signal. 2014;7:ra31 pubmed publisher |
| Chaudhuri D, Sancak Y, Mootha V, Clapham D. MCU encodes the pore conducting mitochondrial calcium currents. elife. 2013;2:e00704 pubmed publisher |
