This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Fbxw7 antibody
catalog :
Ab109617
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5h
  • western blot; human; 1:1000; loading ...; fig 5h
Liu L, Tao T, Liu S, Yang X, Chen X, Liang J, et al. An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness. Nat Commun. 2021;12:2693 pubmed publisher
  • western blot; human; loading ...; fig 4d
Huang Y, Cai K, Xu P, Wang L, Huang C, Fang Y, et al. CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis. Signal Transduct Target Ther. 2021;6:10 pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig 6a
Ailiken G, Kitamura K, Hoshino T, Satoh M, Tanaka N, Minamoto T, et al. Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer. Oncogenesis. 2020;9:26 pubmed publisher
  • western blot; human; loading ...; fig s2a
Gómez Pastor R, Burchfiel E, Neef D, Jaeger A, Cabiscol E, McKinstry S, et al. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nat Commun. 2017;8:14405 pubmed publisher
  • western blot; mouse; fig 4e
Wakatsuki S, Tokunaga S, Shibata M, Araki T. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017;216:477-493 pubmed publisher
Shang C, Lai J, Haque M, Chen W, Wang P, Lai R. Nuclear NPM-ALK Protects Myc from Proteasomal Degradation and Contributes to Its High Expression in Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma. Int J Mol Sci. 2023;24: pubmed publisher
Li S, Deng J, Sun D, Chen S, Yao X, Wang N, et al. FBXW7 alleviates hyperglycemia-induced endothelial oxidative stress injury via ROS and PARP inhibition. Redox Biol. 2022;58:102530 pubmed publisher
Yu X, Zhou L, Liu W, Liu L, Gao F, Li W, et al. Skp2 stabilizes Mcl-1 and confers radioresistance in colorectal cancer. Cell Death Dis. 2022;13:249 pubmed publisher
Hagiwara M, Fushimi A, Bhattacharya A, Yamashita N, Morimoto Y, Oya M, et al. MUC1-C integrates type II interferon and chromatin remodeling pathways in immunosuppression of prostate cancer. Oncoimmunology. 2022;11:2029298 pubmed publisher
Mun G, Choi E, Lee Y, Lee Y. Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1. Cell Death Dis. 2020;11:395 pubmed publisher
Huang L, Zhao J, Chen H, Wan L, Inuzuka H, Guo J, et al. SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nat Commun. 2018;9:3569 pubmed publisher
product information
CatalogNumber :
ab109617
ItemName :
Anti-Fbxw7 antibody
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
100 µg
SpeciesSummary :
Hu
Purity :
Immunogen affinity purified
Application Summary :
ICC/IF, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK