This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-CGRP antibody [4901]
catalog :
AB81887
quantity :
100µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4901
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section, other
citations: 39
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1a, 4j
Hu B, Lv X, Wei L, Wang Y, Zheng G, Yang C, et al. Sensory Nerve Maintains Intervertebral Disc Extracellular Matrix Homeostasis Via CGRP/CHSY1 Axis. Adv Sci (Weinh). 2022;9:e2202620 pubmed publisher
  • other; rat; loading ...; fig s3a
  • immunohistochemistry - frozen section; rat; loading ...; fig s3d
Rees T, Russo A, O Carroll S, Hay D, Walker C. CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons. Front Physiol. 2022;13:860037 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...
Lv X, Gao F, LI T, Xue P, Wang X, Wan M, et al. Skeleton interoception regulates bone and fat metabolism through hypothalamic neuroendocrine NPY. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 7a
Keil Stietz K, Kennedy C, Sethi S, Valenzuela A, Nunez A, Wang K, et al. In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder. Curr Res Toxicol. 2021;2:1-18 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 3a
Yang H, Jhang J, Hsu Y, Jiang Y, Zhai W, Kuo H. Smaller bladder capacity and stronger bladder contractility in patients with ketamine cystitis are associated with elevated TRPV1 and TRPV4. Sci Rep. 2021;11:5200 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 2a
Sun Q, Zhen G, LI T, Guo Q, Li Y, Su W, et al. Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2d
Qi L, Yin G, Zhang Y, Tao Y, Wu X, Gronostajski R, et al. Nuclear Factor I/A Controls A-fiber Nociceptor Development. Neurosci Bull. 2020;36:685-695 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 5d
Cheng W, Gonzalez I, Pan W, Tsang A, Adams J, Ndoka E, et al. Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding. Cell Metab. 2020;31:301-312.e5 pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 2b
Wang H, Wei Y, Pu Y, Jiang D, Jiang X, Zhang Y, et al. Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity. Sci Signal. 2019;12: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 10a
Kaestner C, Smith E, Peirce S, Hoover D. Immunohistochemical analysis of the mouse celiac ganglion: An integrative relay station of the peripheral nervous system. J Comp Neurol. 2019;: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1a
Chen H, Hu B, Lv X, Zhu S, Zhen G, Wan M, et al. Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis. Nat Commun. 2019;10:181 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s1c
Rowe A, Yun H, Treat B, Kinchington P, Hendricks R. Subclinical Herpes Simplex Virus Type 1 Infections Provide Site-Specific Resistance to an Unrelated Pathogen. J Immunol. 2017;198:1706-1717 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:10,000; loading ...; fig 5i
Mei F, Lehmann Horn K, Shen Y, Rankin K, Stebbins K, Lorrain D, et al. Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery. elife. 2016;5: pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig 2b
Matynia A, Nguyen E, Sun X, Blixt F, Parikh S, Kessler J, et al. Peripheral Sensory Neurons Expressing Melanopsin Respond to Light. Front Neural Circuits. 2016;10:60 pubmed publisher
  • immunohistochemistry; mouse; 1:5000; loading ...; fig s4
Roman C, Derkach V, Palmiter R. Genetically and functionally defined NTS to PBN brain circuits mediating anorexia. Nat Commun. 2016;7:11905 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:400; fig 1b
Mambretti E, Kistner K, Mayer S, Massotte D, Kieffer B, Hoffmann C, et al. Functional and structural characterization of axonal opioid receptors as targets for analgesia. Mol Pain. 2016;12: pubmed publisher
  • western blot; mouse; 1:1000
Kim Y, Kim T, McKemy D, Bae Y. Expression of vesicular glutamate transporters in transient receptor potential melastatin 8 (TRPM8)-positive dental afferents in the mouse. Neuroscience. 2015;303:378-88 pubmed publisher
  • immunohistochemistry; mouse; 1:1000
Szabo N, Da Silva R, Sotocinal S, Zeilhofer H, Mogil J, Kania A. Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity, and nociception. J Neurosci. 2015;35:5233-46 pubmed publisher
  • immunohistochemistry; rat; 1:1000
  • immunohistochemistry; mouse; 1:1000
Li Y, Korgaonkar A, Swietek B, Wang J, Elgammal F, Elkabes S, et al. Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury. Neurobiol Dis. 2015;74:240-53 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig  4
Syhr K, Kallenborn Gerhardt W, Lu R, Olbrich K, Schmitz K, Männich J, et al. Lack of effect of a P2Y6 receptor antagonist on neuropathic pain behavior in mice. Pharmacol Biochem Behav. 2014;124:389-95 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Sábado J, Casanovas A, Tarabal O, Hereu M, Piedrafita L, Caldero J, et al. Accumulation of misfolded SOD1 in dorsal root ganglion degenerating proprioceptive sensory neurons of transgenic mice with amyotrophic lateral sclerosis. Biomed Res Int. 2014;2014:852163 pubmed publisher
  • immunohistochemistry; mouse
Waber Wenger B, Forterre F, Kuehni Boghenbor K, Danuser R, Stein J, Stoffel M. Sensory innervation of the dorsal longitudinal ligament and the meninges in the lumbar spine of the dog. Histochem Cell Biol. 2014;142:433-47 pubmed publisher
  • immunohistochemistry; rat; 1:80
Shenton F, Pyner S. Expression of transient receptor potential channels TRPC1 and TRPV4 in venoatrial endocardium of the rat heart. Neuroscience. 2014;267:195-204 pubmed publisher
Chen H, Gardner E, Shah Y, Zhang K, Thakur A, Zhang C, et al. FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS. bioRxiv. 2023;: pubmed publisher
Arthurs J, Pauli J, Palmiter R. Activation of Parabrachial Tachykinin 1 Neurons Counteracts Some Behaviors Mediated by Parabrachial Calcitonin Gene-related Peptide Neurons. Neuroscience. 2023;517:105-116 pubmed publisher
Alarc xf3 n Alarc xf3 n D, Caba xf1 ero D, de Andr xe9 s L xf3 pez J, Nikolaeva Koleva M, Giorgi S, Fern xe1 ndez Ballester G, et al. TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine. Nat Commun. 2022;13:6304 pubmed publisher
Pollard K, Bowser D, Anderson W, Meselhe M, Moore M. Morphine-sensitive synaptic transmission emerges in embryonic rat microphysiological model of lower afferent nociceptive signaling. Sci Adv. 2021;7: pubmed publisher
Kucharczyk M, Chisholm K, Denk F, Dickenson A, Bannister K, McMahon S. The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli. Pain. 2020;161:1894-1905 pubmed publisher
Li Q, Zhu Z, Lu J, Chao Y, Zhou X, Huang Y, et al. Sleep deprivation of rats increases postsurgical expression and activity of L-type calcium channel in the dorsal root ganglion and slows recovery from postsurgical pain. Acta Neuropathol Commun. 2019;7:217 pubmed publisher
Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed publisher
Huang Y, Klingbeil O, He X, Wu X, Arun G, Lu B, et al. POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev. 2018;32:915-928 pubmed publisher
Tian N, Xu Y, Yang J, Li L, Sun X, Wang Y, et al. KChIP3 N-Terminal 31-50 Fragment Mediates Its Association with TRPV1 and Alleviates Inflammatory Hyperalgesia in Rats. J Neurosci. 2018;38:1756-1773 pubmed publisher
Ryan P, Ross S, Campos C, Derkach V, Palmiter R. Oxytocin-receptor-expressing neurons in the parabrachial nucleus regulate fluid intake. Nat Neurosci. 2017;20:1722-1733 pubmed publisher
Li Z, Li Y, Cao J, Han X, Cai W, Zang W, et al. Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model. BMC Anesthesiol. 2017;17:150 pubmed publisher
He W, Wang X, Shi H, Bai W, Cheng B, Su Y, et al. Cutaneous neurogenic inflammation in the sensitized acupoints induced by gastric mucosal injury in rats. BMC Complement Altern Med. 2017;17:141 pubmed publisher
Driessen A, Farrell M, Mazzone S, McGovern A. The Role of the Paratrigeminal Nucleus in Vagal Afferent Evoked Respiratory Reflexes: A Neuroanatomical and Functional Study in Guinea Pigs. Front Physiol. 2015;6:378 pubmed publisher
Thakur M, Crow M, Richards N, Davey G, Levine E, Kelleher J, et al. Defining the nociceptor transcriptome. Front Mol Neurosci. 2014;7:87 pubmed publisher
Ruiz E, Oeztuerk Winder F, Ventura J. A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nat Commun. 2014;5:3175 pubmed publisher
Eftekhari S, Edvinsson L. Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level. BMC Neurosci. 2011;12:112 pubmed publisher
product information
Catalog Number :
ab81887
Product Name :
Anti-CGRP antibody [4901]
Product Type :
Primary Antibody
Swiss-Prot ID :
P01256
Host Species :
Mouse
Clonality :
Monoclonal
Size :
100µL
Application Summary :
Flow Cyt, ICC/IF, IHC-Fr
Isotype :
IgG2a
Reactivity :
Guinea pig, Human, Mouse, Rat
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK