This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Tyrosine Hydroxylase antibody - Neuronal Marker
catalog :
AB76442
quantity :
250µL
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 33
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig s7b
Zhang D, Yamaguchi S, Zhang X, Yang B, Kurooka N, Sugawara R, et al. Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control. Front Endocrinol (Lausanne). 2021;12:727915 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 7d
Albanese F, Mercatelli D, Finetti L, Lamonaca G, Pizzi S, Shimshek D, et al. Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Neurobiol Dis. 2021;159:105487 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4d
Scherschel K, Bräuninger H, Mölders A, Erlenhardt N, Amin E, Jungen C, et al. Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6??s2a
Courtland J, Bradshaw T, Waitt G, Soderblom E, Ho T, Rajab A, et al. Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig 3c
Ryan B, Bengoa Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, et al. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model. J Neurosci. 2021;: pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 3a
Lisieski M, Karavidha K, Gheidi A, Garibyan R, Conti A, Morrow J, et al. Divergent effects of repeated cocaine and novel environment exposure on locus coeruleus c-fos expression and brain catecholamine concentrations in rats. Brain Behav. 2019;9:e01222 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 7b
Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000
Peris J, Macfadyen K, Smith J, de Kloet A, Wang L, Krause E. Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic targets. J Comp Neurol. 2017;525:1094-1108 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 4
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 4
Hughes S, Rodgers J, Hickey D, Foster R, Peirson S, Hankins M. Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways. Sci Rep. 2016;6:28086 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:400; fig 1
Morales I, Sánchez A, Rodriguez Sabate C, Rodriguez M. The astrocytic response to the dopaminergic denervation of the striatum. J Neurochem. 2016;139:81-95 pubmed publisher
  • immunohistochemistry - free floating section; mouse; fig s16
Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016;7:10332 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
De Luca R, Suvorava T, Yang D, Baumgärtel W, Kojda G, Haas H, et al. Identification of histaminergic neurons through histamine 3 receptor-mediated autoinhibition. Neuropharmacology. 2016;106:102-15 pubmed publisher
Strong C, Zhang J, Carrasco M, Kundu S, Boutin M, Vishwasrao H, et al. Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening. Commun Biol. 2023;6:1211 pubmed publisher
Sela M, Poley M, Mora Raimundo P, Kagan S, Avital A, Kaduri M, et al. Brain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease. Adv Mater. 2023;35:e2304654 pubmed publisher
Chao C, Huang C, Cheng J, Chiou C, Lee I, Yang Y, et al. SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease. Redox Biol. 2022;58:102534 pubmed publisher
Kofoed R, Noseworthy K, Wu K, Sivadas S, Stanek L, Elmer B, et al. The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites. Mol Ther Methods Clin Dev. 2022;27:167-184 pubmed publisher
Koba S, Kumada N, Narai E, Kataoka N, Nakamura K, Watanabe T. A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses. Nat Commun. 2022;13:5079 pubmed publisher
Yang Y, He Y, Liu H, Zhou W, Wang C, Xu P, et al. Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Rep. 2021;37:110075 pubmed publisher
Wang Y, Pang J, Wang Q, Yan L, Wang L, Xing Z, et al. Delivering Antisense Oligonucleotides across the Blood-Brain Barrier by Tumor Cell-Derived Small Apoptotic Bodies. Adv Sci (Weinh). 2021;8:2004929 pubmed publisher
Liu X, Wang Q, Yang Y, Stewart T, Shi M, Soltys D, et al. Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease. Acta Neuropathol Commun. 2021;9:37 pubmed publisher
Bengoa Vergniory N, Faggiani E, Ramos Gonzalez P, Kirkiz E, Connor Robson N, Brown L, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nat Commun. 2020;11:4885 pubmed publisher
Kabayama H, Takeuchi M, Tokushige N, Muramatsu S, Kabayama M, Fukuda M, et al. An ultra-stable cytoplasmic antibody engineered for in vivo applications. Nat Commun. 2020;11:336 pubmed publisher
Mazzocchi M, Wyatt S, Mercatelli D, Morari M, Morales Prieto N, Collins L, et al. Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling. Front Cell Dev Biol. 2019;7:191 pubmed publisher
Paul E, Kalk E, Tossell K, Irvine E, Franks N, Wisden W, et al. nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta. Eneuro. 2018;5: pubmed publisher
Han W, Tellez L, Perkins M, Perez I, Qu T, Ferreira J, et al. A Neural Circuit for Gut-Induced Reward. Cell. 2018;175:665-678.e23 pubmed publisher
Koba S, Hanai E, Kumada N, Kataoka N, Nakamura K, Watanabe T. Sympathoexcitation by hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla. J Physiol. 2018;596:4581-4595 pubmed publisher
Blaudin de Thé F, Rekaik H, Peze Heidsieck E, Massiani Beaudoin O, Joshi R, Fuchs J, et al. Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression. EMBO J. 2018;37: pubmed publisher
Li S, Vaughan A, Sturgill J, Kepecs A. A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons. Neuron. 2018;98:905-917.e5 pubmed publisher
Wang L, Hong J, Wu Y, Liu G, Yu W, Chen L. Seipin deficiency in mice causes loss of dopaminergic neurons via aggregation and phosphorylation of ?-synuclein and neuroinflammation. Cell Death Dis. 2018;9:440 pubmed publisher
Hammond S, Popichak K, Li X, Hunt L, Richman E, Damale P, et al. The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism. J Pharmacol Exp Ther. 2018;365:636-651 pubmed publisher
Johnson E, Westbrook T, Shayesteh R, Chen E, Schumacher J, Fitzpatrick D, et al. Distribution and diversity of intrinsically photosensitive retinal ganglion cells in tree shrew. J Comp Neurol. 2019;527:328-344 pubmed publisher
Bal N, Singh S, Reis F, Maurya S, Pani S, Rowland L, et al. Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice. J Biol Chem. 2017;292:16616-16625 pubmed publisher
product information
Catalog Number :
ab76442
Product Name :
Anti-Tyrosine Hydroxylase antibody - Neuronal Marker
Product Type :
Primary Antibody
Swiss-Prot ID :
P07101
Host Species :
Chicken
Clonality :
Polyclonal
Size :
250µL
Application Summary :
IHC-FrFl, IHC-P
Isotype :
IgY
Reactivity :
Mouse
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK