This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-CHD4 antibody [3F2/4]
catalog :
AB70469
quantity :
100µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3F2/4
reactivity :
human, mouse
application :
western blot, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s5a
  • western blot; mouse; 1:1000; loading ...; fig 5b
Ma L, Xie D, Luo M, Lin X, Nie H, Chen J, et al. Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis. Sci Adv. 2022;8:eabn1606 pubmed publisher
  • ChIP-Seq; mouse; loading ...; fig 5b
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 1a
de Castro R, Carbajal A, Previato de Almeida L, Goitea V, Griffin C, Pezza R. Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development. Epigenetics Chromatin. 2022;15:16 pubmed publisher
  • western blot; mouse; loading ...
Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez Priego C, et al. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Cell Stem Cell. 2020;26:234-250.e7 pubmed publisher
  • western blot; mouse; loading ...; fig s1b
Yen W, Sharma R, Cols M, Lau C, Chaudhry A, Chowdhury P, et al. Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Rep. 2019;27:1472-1486.e5 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Mol Cell. 2018;71:56-72.e4 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 4d
Liang Z, Brown K, Carroll T, Taylor B, Vidal I, Hendrich B, et al. A high-resolution map of transcriptional repression. elife. 2017;6: pubmed publisher
  • western blot; mouse; fig 8d
Minnich M, Tagoh H, Bönelt P, Axelsson E, Fischer M, Cebolla B, et al. Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation. Nat Immunol. 2016;17:331-43 pubmed publisher
de la Cruz Herrera C, Tatham M, Siddiqi U, Shire K, Marcon E, Greenblatt J, et al. Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1. PLoS Pathog. 2023;19:e1011477 pubmed publisher
Schmolka N, Karemaker I, Cardoso da Silva R, Recchia D, Spegg V, Bhaskaran J, et al. Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation. Nat Commun. 2023;14:3848 pubmed publisher
El Abdellaoui Soussi F, Yunes Leites P, L xf3 pez Maderuelo D, Garc xed a Marqu xe9 s F, V xe1 zquez J, Redondo J, et al. Interplay between the Chd4/NuRD Complex and the Transcription Factor Znf219 Controls Cardiac Cell Identity. Int J Mol Sci. 2022;23: pubmed publisher
Garipler G, Lu C, Morrissey A, Lopez Zepeda L, Pei Y, Vidal S, et al. The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes. Cell Rep. 2022;38:110524 pubmed publisher
Hirota A, Nakajima Koyama M, Ashida Y, Nishida E. The nucleosome remodeling and deacetylase complex protein CHD4 regulates neural differentiation of mouse embryonic stem cells by down-regulating p53. J Biol Chem. 2019;294:195-209 pubmed publisher
Zhao Z, Sentürk N, Song C, Grummt I. lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures. Genes Dev. 2018;32:836-848 pubmed publisher
Kim M, Kim J, Son S, Lim C, Eum H, Ha D, et al. Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis. Nucleic Acids Res. 2018;46:4933-4949 pubmed publisher
product information
Catalog Number :
ab70469
Product Name :
Anti-CHD4 antibody [3F2/4]
Product Type :
Primary Antibody
Swiss-Prot ID :
Q14839
Host Species :
Mouse
Clonality :
Monoclonal
Size :
100µg
Application Summary :
IHC-P
Isotype :
IgG1
Reactivity :
Human
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK