This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Nestin antibody [Rat-401] - Neural Stem Cell Marker
catalog :
AB6142
quantity :
100µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Rat 401
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, mass cytometry
citations: 34
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s4a
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s12c
Welch G, Boix C, Schmauch E, Davila Velderrain J, Victor M, Dileep V, et al. Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Sci Adv. 2022;8:eabo4662 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1b, 4a
Moore A, Chinnaiya K, Kim D, Brown S, Stewart I, Robins S, et al. Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes. Front Neurosci. 2022;16:832961 pubmed publisher
  • immunohistochemistry; rat; 1:200; loading ...; fig 5c
McClenahan F, Dimitriou C, Koutsakis C, Dimitrakopoulos D, Arampatzis A, Kakouri P, et al. Isolation of neural stem and oligodendrocyte progenitor cells from the brain of live rats. Stem Cell Reports. 2021;16:2534-2547 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1a
  • immunohistochemistry; mouse; loading ...; fig 3a
Morales Garcia J, Calleja Conde J, Lopez Moreno J, Alonso Gil S, Sanz Sancristobal M, Riba J, et al. N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo. Transl Psychiatry. 2020;10:331 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s14a, s14b
Kim J, Fei L, Yin W, Coquenlorge S, Rao Bhatia A, Zhang X, et al. Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun. 2020;11:334 pubmed publisher
  • immunocytochemistry; mouse; 1:300; loading ...; fig 1a
Zhu Q, Zhang N, Hu N, Jiang R, Lu H, Xuan A, et al. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Mol Med Rep. 2020;21:1172-1180 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig 3a
Li J, Liu Z, Wang L, Xu H, Wang Y. Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors. Biosci Rep. 2019;39: pubmed publisher
  • mass cytometry; mouse; loading ...; fig 1d
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 2a
Yang X, Ding Y, Yang M, Yu L, Hu Y, Deng Y. Nestin Improves Preeclampsia-Like Symptoms by Inhibiting Activity of Cyclin-Dependent Kinase 5. Kidney Blood Press Res. 2018;43:616-627 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 1b
Ziaee S, Tabeshmehr P, Haider K, Farrokhi M, Shariat A, Amiri A, et al. Optimization of time for neural stem cells transplantation for brain stroke in rats. Stem Cell Investig. 2017;4:29 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100
  • immunocytochemistry; human; 1:100; fig e5a
Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed publisher
Williamson M, Le S, Franzen R, Donlan N, Rosow J, Nicot Cartsonis M, et al. Subventricular zone cytogenesis provides trophic support for neural repair in a mouse model of stroke. Nat Commun. 2023;14:6341 pubmed publisher
Gil N, Perry R, Mukamel Z, Tuck A, B xfc hler M, Ulitsky I. Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus. Cell Rep. 2023;42:112569 pubmed publisher
Liu H, Wang C, Yi F, Yeo S, Haas M, Tang X, et al. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Sci Rep. 2021;11:23907 pubmed publisher
Takanezawa Y, Tanabe S, Kato D, Ozeki R, Komoda M, Suzuki T, et al. Microglial ASD-related genes are involved in oligodendrocyte differentiation. Sci Rep. 2021;11:17825 pubmed publisher
Song L, Tian X, Schekman R. Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1. J Cell Biol. 2021;220: pubmed publisher
Giraldo E, Palmero Canton D, Martinez Rojas B, Sánchez Martín M, Moreno Manzano V. Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential. Int J Mol Sci. 2020;22: pubmed publisher
Lohrberg M, Winkler A, Franz J, van der Meer F, Ruhwedel T, Sirmpilatze N, et al. Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination. Acta Neuropathol Commun. 2020;8:224 pubmed publisher
Hezroni H, Ben Tov Perry R, Gil N, Degani N, Ulitsky I. Regulation of neuronal commitment in mouse embryonic stem cells by the Reno1/Bahcc1 locus. EMBO Rep. 2020;21:e51264 pubmed publisher
Will L, Portegies S, van Schelt J, van Luyk M, Jaarsma D, Hoogenraad C. Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo. Acta Neuropathol Commun. 2019;7:162 pubmed publisher
Zhang J, He L, Yang Z, Li L, Cai W. Lithium chloride promotes proliferation of neural stem cells in vitro, possibly by triggering the Wnt signaling pathway. Anim Cells Syst (Seoul). 2019;23:32-41 pubmed publisher
Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed publisher
Weise S, Villarreal A, Heidrich S, Dehghanian F, Schachtrup C, Nestel S, et al. TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain. Front Cell Neurosci. 2018;12:448 pubmed publisher
Wang C, Jégu T, Chu H, Oh H, Lee J. SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X. Cell. 2018;174:406-421.e25 pubmed publisher
Alamir H, Alomari M, Salwati A, Saka M, Bangash M, Baeesa S, et al. In situ characterization of stem cells-like biomarkers in meningiomas. Cancer Cell Int. 2018;18:77 pubmed publisher
Liu Y, Wang D, Yang Y, Lei W. Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia. BMC Anesthesiol. 2017;17:117 pubmed publisher
Khan I, Baeesa S, Bangash M, Schulten H, Alghamdi F, Qashqari H, et al. Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines. Cancer Cell Int. 2017;17:72 pubmed publisher
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras C, et al. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells. BMC Cancer. 2017;17:488 pubmed publisher
Qi Q, Kang S, Zhang S, Pham C, Fu H, Brat D, et al. Co-amplification of phosphoinositide 3-kinase enhancer A and cyclin-dependent kinase 4 triggers glioblastoma progression. Oncogene. 2017;36:4562-4572 pubmed publisher
Webster M, Cooley Themm C, Barnett J, Bach H, Vainner J, Webster S, et al. Evidence of BrdU-positive retinal neurons after application of an Alpha7 nicotinic acetylcholine receptor agonist. Neuroscience. 2017;346:437-446 pubmed publisher
Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
Esanov R, Belle K, van Blitterswijk M, Belzil V, Rademakers R, Dickson D, et al. C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Exp Neurol. 2016;277:171-177 pubmed publisher
Kotterman M, Vazin T, Schaffer D. Enhanced selective gene delivery to neural stem cells in vivo by an adeno-associated viral variant. Development. 2015;142:1885-92 pubmed publisher
Mich J, Signer R, Nakada D, Pineda A, Burgess R, Vue T, et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. elife. 2014;3:e02669 pubmed publisher
product information
Catalog Number :
ab6142
Product Name :
Anti-Nestin antibody [Rat-401] - Neural Stem Cell Marker
Product Type :
Primary Antibody
Swiss-Prot ID :
Q6P5H2
Host Species :
Mouse
Clonality :
Monoclonal
Size :
100µg
Application Summary :
IHC-P, WB
Isotype :
IgG1
Reactivity :
Mouse, Rat
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK