Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC) Antibody (FITC)

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product summary

company name :

Abbexa

product type :

antibody

product name :

Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC) Antibody (FITC)

catalog :

abx200310

quantity :

100 tests

price :

406 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

abx200310

Target :

Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC)

Product Name :

Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC) Antibody (FITC)

Short Name :

PTPRC

Long Name :

Protein Tyrosine Phosphatase Receptor Type C / CD45

Product Type :

Primary Antibodies

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

FITC

Isotype :

IgG1

Size 1 :

100 tests

List Price 1 (USD) :

406 USD

Swiss Prot :

P08575

Swiss Prot Entry Name :

PTPRC_HUMAN

KEGG :

hsa:5788

String :

9606.ENSP00000411355

Product Description :

The CD45 molecule is also known as the Leukocyte Common Antigen (LCA) or T200 antigen, and is comprised of different glycoproteins ranging from 180-240 kDa. Expression of CD45 is found on all hemopoietic cells, e.g. granulocytes, monocytes, macrophages and lymphocytes, except mature erythroid cells. Detection of the different isoforms can distinguish, for example, between naive T cells and memory T cells, which is of interest in patients with immunodeficiency and autoimmune diseases.

CrossReactivity :

Human

ALTnames :

PTPRC, Protein Tyrosine Phosphatase, Receptor Type C, CD45 Antigen, CD45, L-CA, T200, Protein Tyrosine Phosphatase, Receptor Type, C Polypeptide, Receptor-Type Tyrosine-Protein Phosphatase C, T200 Leukocyte Common Antigen, Leukocyte Common Antigen, Protein Tyrosine Phosphatase Receptor Type C, PTPR-C, LCA, B220, GP180, LY5, CD45R, CD45RA, CD45RB, CD45RC, CD45RO, CD45R0, L-CA, CD45RABC, CD45RAB, CD45RAC, CD45RBC

Immunogen :

Human Peripheral Blood Leucocytes.

Specificity :

The CD45 (HI30) antibody recognizes the 180, 190, 205 and 220-kDa long single chain type I transmembrane glycoprotein called leukocyte common antigen (LCA). LCA is typically expressed at high levels on all nucleated hematopoietic cells including bone marrow cells, thymocytes, lymphocytes, monocytes, granulocytes, but not on mature erythrocytes, platelets and non-hematopoietic tissues and cells. CD45 is critically required for T and B cell antigen receptor-mediated activation.

Purification :

Affinity Chromatography

Buffer :

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide

Application Summary :

FCM

Storage :

Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.

Form :

Liquid

UNSPSC Code :

12352203

Molecular Weight :

180-220 kDa

Availability :

Shipped within 3-5 working days.

Note :

This product is for research use only.