This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
protein
product name :
Human Superoxide Dismutase 1 (SOD1) Protein (Active)
catalog :
abx060221
quantity :
100 µg
product information
Catalogue Code :
abx060221
Target :
Superoxide Dismutase 1 (SOD1)
Product Name :
Human Superoxide Dismutase 1 (SOD1) Protein (Active)
Short Name :
SOD1
Category :
Proteins and Peptides
Host :
E. coli
Conjugation :
Unconjugated
Size 1 :
100 µg
Size 2 :
1 mg
Size 3 :
2 mg
Size 4 :
3.75 mg
Description :
Human SOD Protein is a recombinant protein expressed in E. coli. Superoxide dismutases (SOD) are enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Thus, they are an important antioxidant defense in nearly all cells exposed to oxygen. Several common forms of SOD exist: they are proteins cofactored with copper and zinc, or manganese, iron, or nickel. Thus, there are three major families of superoxide dismutase, depending on the metal cofactor: Cu/Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and the Ni type, which binds nickel. Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mutations in the first SOD enzyme (SOD1) can cause familial amyotrophic lateral sclerosis (ALS, a form of motor neuron disease). The other two isoforms of SOD have not been linked to any human diseases, however, in mice inactivation of SOD2 causes perinatal lethality and inactivation of SOD1 causes hepatocellular carcinoma.
UniProt Primary AC :
P00441
UniProt Entry Name :
SODC_HUMAN
OMIM :
147450
KEGG :
hsa:6647
String :
9606.ENSP00000270142
Purity :
> 95% (HPLC and SDS-PAGE). Contains < 1% Dimers (SDS-PAGE)
Buffer :
Prior to lyophilization: 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0). Does not contain preservatives.
Tested Applications :
SDS-PAGE
Activity :
Active
Storage :
Aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze/thaw cycles.
Form :
Lyophilized
UNSPSC Code :
12352202
Origin :
Human
Expression :
Recombinant
Availability :
Shipped within 5-10 working days.
DryIce :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.