This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
antibody
product name :
Histone H2A.X (H2AFX) Antibody
catalog :
abx034795
quantity :
50 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
Catalogue Code :
abx034795
Target :
Histone H2A.X (H2AFX)
Product Name :
Histone H2A.X (H2AFX) Antibody
Short Name :
H2AFX
Category :
Primary Antibodies
Host :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Isotype :
IgG1
Size 1 :
50 µl
Size 2 :
200 µl
Description :
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UniProt Primary AC :
P16104
UniProt Entry Name :
H2AX_HUMAN
NCBI Accession :
NP_002096.1
KEGG :
hsa:3014
String :
9606.ENSP00000434024
Purification :
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Buffer :
PBS containing 0.09% sodium azide.
Tested Applications :
ELISA, WB, IHC
Storage :
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Form :
Liquid
UNSPSC Code :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.