This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
antibody
product name :
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody
catalog :
abx030710
quantity :
80 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
application :
western blot, ELISA
product information
Catalogue Code :
abx030710
Target :
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Product Name :
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody
Short Name :
FZR1
Category :
Primary Antibodies
Host :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size 1 :
80 µl
Size 2 :
400 µl
Description :
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
UniProt Primary AC :
Q9UM11
UniProt Entry Name :
FZR1_HUMAN
Gene Symbol :
FZR1
String :
9606.ENSP00000378529
Purification :
Purified through a protein A column, followed by peptide affinity purification.
Buffer :
PBS containing 0.09% sodium azide.
Tested Applications :
ELISA, WB
Storage :
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Form :
Liquid
UNSPSC Code :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.