F-Box Protein 11 (FBXO11) Antibody | Abbexa abx029150 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Abbexa

product type :

antibody

product name :

F-Box Protein 11 (FBXO11) Antibody

catalog :

abx029150

quantity :

80 µl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Catalogue Code :

abx029150

Target :

F-Box Protein 11 (FBXO11)

Product Name :

F-Box Protein 11 (FBXO11) Antibody

Short Name :

FBXO11

Category :

Primary Antibodies

Host :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size 1 :

80 µl

Size 2 :

400 µl

Description :

This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

UniProt Primary AC :

Q86XK2

UniProt Entry Name :

FBX11_HUMAN

Gene Symbol :

FBXO11

KEGG :

hsa:80204

String :

9606.ENSP00000384823

Purification :

Purified through a protein A column, followed by peptide affinity purification.

Buffer :

PBS containing 0.09% sodium azide.

Tested Applications :

ELISA, WB

Storage :

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Form :

Liquid

UNSPSC Code :

12352203

Availability :

Please enquire.

DryIce :