This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
antibody
product name :
Caspase 8 (CASP8) Antibody
catalog :
abx012068
quantity :
100 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry
product information
Catalogue Code :
abx012068
Target :
Caspase 8 (CASP8)
Product Name :
Caspase 8 (CASP8) Antibody
Short Name :
CASP8
Category :
Primary Antibodies
Host :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Isotype :
IgG1
Size 1 :
100 µl
Description :
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Alternative splicing of this gene results in five transcript variants.
UniProt Primary AC :
Q14790
UniProt Entry Name :
CASP8_HUMAN
KEGG :
hsa:841
String :
9606.ENSP00000351273
Purification :
Unpurified ascites.
Buffer :
Ascitic fluid containing 0.03% sodium azide.
Concentration :
Not determined
Tested Applications :
ELISA, WB, IHC, FCM
Storage :
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Form :
Liquid
UNSPSC Code :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.