This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
antibody
product name :
GR (pS203) Antibody
catalog :
abx011847
quantity :
10 µg
price :
43.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
Catalog Number :
abx011847
Target :
GR (pS203)
Product Name :
GR (pS203) Antibody
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Size 1 :
10 µg
Size 2 :
20 µg
Size 3 :
100 µg
Price 1 (USD) :
43.5 USD
Price 2 (USD) :
87
Price 3 (USD) :
406
Product Description :
Phospho-GR (Ser203) Antibody detects endogenous levels of GR only when phosphorylated at Sersine 203. The protein encoded by this gene is a receptor for glucocorticoids and can act as both a transcription factor and a regulator of other transcription factors. The encoded protein can bind DNA as a homodimer or as a heterodimer with another protein such as the retinoid X receptor. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
UniProt Primary AC :
P04150
UniProt Entry Name :
GCR_HUMAN
Gene Symbol :
NR3C1
OMIM :
138040
HGNC :
7978
Ensembl :
ENSG00000113580
String :
9606.ENSP00000231509
CrossReactivity :
Human, Mouse
Purification :
Purified by affinity chromatography.
Buffer :
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications :
WB
Storage :
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code :
12352203
Availability :
Shipped within 5-10 working days.
Note :
This product is for research use only.
Dry Ice :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.