This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abbexa
product type :
antibody
product name :
Plasma Kallikrein (KLKB1) Antibody
catalog :
abx004066
quantity :
60 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Catalogue Code :
abx004066
Target :
Plasma Kallikrein (KLKB1)
Product Name :
Plasma Kallikrein (KLKB1) Antibody
Short Name :
KLKB1
Category :
Primary Antibodies
Host :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size 1 :
60 µl
Size 2 :
120 µl
Size 3 :
200 µl
Description :
KLKB1 Antibody is a Rabbit Polyclonal antibody against KLKB1. Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
UniProt Primary AC :
P03952
UniProt Entry Name :
KLKB1_HUMAN
Gene Symbol :
KLKB1
NCBI Accession :
NP_000883.2
KEGG :
hsa:3818
String :
9606.ENSP00000264690
Purification :
Purified by affinity chromatography.
Buffer :
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration :
1 mg/ml
Tested Applications :
WB, IHC
Storage :
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Form :
Liquid
UNSPSC Code :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
company information
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
headquarters: UK
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.