product summary
company name :
ALPCO
product type :
ELISA/assay
product name :
Mouse Ultrasensitive Insulin ELISA
catalog :
80-INSMSU-E01
quantity :
96 Wells
price :
399.00 USD
more info or order :
citations: 48
Reference
Hilgendorf K, Johnson C, Mezger A, Rice S, Norris A, Demeter J, et al. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019;179:1289-1305.e21 pubmed publisher
Lee C, Kim H, Lee Y, Kang G, Lim H, Lee S, et al. Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation. Cell Rep. 2018;25:934-946.e5 pubmed publisher
Burke A, Sutherland B, Telford D, Morrow M, Sawyez C, Edwards J, et al. Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice. J Lipid Res. 2018;59:1714-1728 pubmed publisher
Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, et al. Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018;24:1058-1069 pubmed publisher
Mühlemann M, Zdzieblo D, Friedrich A, Berger C, Otto C, Walles H, et al. Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet. Mol Metab. 2018;13:67-76 pubmed publisher
Stuhlmann T, Planells Cases R, Jentsch T. LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. Nat Commun. 2018;9:1974 pubmed publisher
Li T, Song L, Sun Y, Li J, Yi C, Lam S, et al. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate. Nat Commun. 2018;9:1916 pubmed publisher
Schneider D, Choi S, Agatisa Boyle C, Zhu L, Kim J, Pattison J, et al. AIBP protects against metabolic abnormalities and atherosclerosis. J Lipid Res. 2018;59:854-863 pubmed publisher
Weis S, Carlos A, Moita M, Singh S, Blankenhaus B, Cardoso S, et al. Metabolic Adaptation Establishes Disease Tolerance to Sepsis. Cell. 2017;169:1263-1275.e14 pubmed publisher
Navarro G, Abdolazimi Y, Zhao Z, Xu H, Lee S, Armstrong N, et al. Genetic Disruption of Adenosine Kinase in Mouse Pancreatic ?-Cells Protects Against High-Fat Diet-Induced Glucose Intolerance. Diabetes. 2017;66:1928-1938 pubmed publisher
Stanley M, Macauley S, Caesar E, Koscal L, Moritz W, Robinson G, et al. The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-? in Young and Old APP/PS1 Mice. J Neurosci. 2016;36:11704-11715 pubmed
Zheng J, Xiao X, Zhang Q, Yu M, Xu J, Qi C, et al. The effects of maternal and post-weaning diet interaction on glucose metabolism and gut microbiota in male mice offspring. Biosci Rep. 2016;36: pubmed publisher
Zheng J, Xiao X, Zhang Q, Yu M, Xu J, Qi C, et al. The programming effects of nutrition-induced catch-up growth on gut microbiota and metabolic diseases in adult mice. Microbiologyopen. 2016;5:296-306 pubmed publisher
Zhu S, Larkin D, Lu S, Inouye C, Haataja L, Anjum A, et al. Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo. Diabetes. 2016;65:699-709 pubmed publisher
Cheng Y, Seibert O, Klöting N, Dietrich A, Straßburger K, Fernández Veledo S, et al. PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis. PLoS Genet. 2015;11:e1005561 pubmed publisher
Jurowich C, Otto C, Rikkala P, Wagner N, Vrhovac I, Sabolić I, et al. Ileal Interposition in Rats with Experimental Type 2 Like Diabetes Improves Glycemic Control Independently of Glucose Absorption. J Diabetes Res. 2015;2015:490365 pubmed publisher
Zheng J, Xiao X, Zhang Q, Yu M, Xu J, Wang Z. Maternal protein restriction induces early-onset glucose intolerance and alters hepatic genes expression in the peroxisome proliferator-activated receptor pathway in offspring. J Diabetes Investig. 2015;6:269-79 pubmed publisher
Zheng J, Xiao X, Zhang Q, Yu M, Xu J, Wang Z, et al. Maternal and post-weaning high-fat, high-sucrose diet modulates glucose homeostasis and hypothalamic POMC promoter methylation in mouse offspring. Metab Brain Dis. 2015;30:1129-37 pubmed publisher
Rajan S, Dickson L, Mathew E, Orr C, Ellenbroek J, Philipson L, et al. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Mol Metab. 2015;4:265-76 pubmed publisher
Wang J, Chakrabarty S, Bui Q, Ruf W, Samad F. Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice. Am J Pathol. 2015;185:524-35 pubmed publisher
Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
Zheng J, Xiao X, Zhang Q, Yu M, Xu J, Wang Z. Maternal high-fat diet modulates hepatic glucose, lipid homeostasis and gene expression in the PPAR pathway in the early life of offspring. Int J Mol Sci. 2014;15:14967-83 pubmed publisher
Yu C, Luo X, Farhat N, Daneault C, Duquette N, Martel C, et al. Lack of angiopoietin-like-2 expression limits the metabolic stress induced by a high-fat diet and maintains endothelial function in mice. J Am Heart Assoc. 2014;3: pubmed publisher
Selfridge J, Wilkins H, E L, Carl S, Koppel S, Funk E, et al. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. J Bioenerg Biomembr. 2015;47:1-11 pubmed publisher
Ishii M, Wang G, Racchumi G, Dyke J, Iadecola C. Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons. J Neurosci. 2014;34:9096-106 pubmed publisher
THRAILKILL K, Bunn R, LUMPKIN C, Wahl E, Cockrell G, Morris L, et al. Loss of insulin receptor in osteoprogenitor cells impairs structural strength of bone. J Diabetes Res. 2014;2014:703589 pubmed publisher
Johnston Cox H, Eisenstein A, Koupenova M, Carroll S, Ravid K. The macrophage A2B adenosine receptor regulates tissue insulin sensitivity. PLoS ONE. 2014;9:e98775 pubmed publisher
Ebrahimie M, Esmaeili F, Cheraghi S, Houshmand F, Shabani L, Ebrahimie E. Efficient and simple production of insulin-producing cells from embryonal carcinoma stem cells using mouse neonate pancreas extract, as a natural inducer. PLoS ONE. 2014;9:e90885 pubmed publisher
Corbin J, Bhaskar V, Goldfine I, Issafras H, Bedinger D, Lau A, et al. Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia. MAbs. 2014;6:262-72 pubmed publisher
Miller R, Harrison D, Astle C, Fernandez E, Flurkey K, Han M, et al. Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction. Aging Cell. 2014;13:468-77 pubmed publisher
Mennes E, Dungan C, Frendo Cumbo S, Williamson D, Wright D. Aging-associated reductions in lipolytic and mitochondrial proteins in mouse adipose tissue are not rescued by metformin treatment. J Gerontol A Biol Sci Med Sci. 2014;69:1060-8 pubmed publisher
Carmean C, Bobe A, Yu J, Volden P, Brady M. Refeeding-induced brown adipose tissue glycogen hyper-accumulation in mice is mediated by insulin and catecholamines. PLoS ONE. 2013;8:e67807 pubmed publisher
Berryman D, Lubbers E, Magon V, List E, Kopchick J. A dwarf mouse model with decreased GH/IGF-1 activity that does not experience life-span extension: potential impact of increased adiposity, leptin, and insulin with advancing age. J Gerontol A Biol Sci Med Sci. 2014;69:131-41 pubmed publisher
Jung C, Kim H, Ahn J, Jeon T, Lee D, Ha T. Fisetin regulates obesity by targeting mTORC1 signaling. J Nutr Biochem. 2013;24:1547-54 pubmed publisher
Jayaram B, Pan W, Wang Y, Hsuchou H, Macé A, Cornelissen Guillaume G, et al. Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity. J Appl Physiol (1985). 2013;114:734-41 pubmed publisher
Delhanty P, Huisman M, Baldéon Rojas L, van den Berge I, Grefhorst A, Abribat T, et al. Des-acyl ghrelin analogs prevent high-fat-diet-induced dysregulation of glucose homeostasis. FASEB J. 2013;27:1690-700 pubmed publisher
Huang C. Wild-type offspring of heterozygous prolactin receptor-null female mice have maladaptive ?-cell responses during pregnancy. J Physiol. 2013;591:1325-38 pubmed publisher
Jung C, Jang S, Ahn J, Gwon S, Jeon T, Kim T, et al. Alpinia officinarum inhibits adipocyte differentiation and high-fat diet-induced obesity in mice through regulation of adipogenesis and lipogenesis. J Med Food. 2012;15:959-67 pubmed publisher
Donato A, Henson G, Morgan R, Enz R, Walker A, Lesniewski L. TNF-? impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity. Am J Physiol Heart Circ Physiol. 2012;303:H672-9 pubmed publisher
Zhang Y, Zhang Y, Bone R, Cui W, Peng J, Siegal G, et al. Regeneration of pancreatic non-? endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin. PLoS ONE. 2012;7:e36675 pubmed publisher
Yang G, Fredholm B, Kieffer T, Kwok Y. Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice. Am J Physiol Endocrinol Metab. 2012;303:E180-90 pubmed publisher
Satyanarayana A, Klarmann K, Gavrilova O, Keller J. Ablation of the transcriptional regulator Id1 enhances energy expenditure, increases insulin sensitivity, and protects against age and diet induced insulin resistance, and hepatosteatosis. FASEB J. 2012;26:309-23 pubmed publisher
Sackmann Sala L, Berryman D, Lubbers E, Vesel C, Troike K, List E, et al. Decreased insulin sensitivity and increased oxidative damage in wasting adipose tissue depots of wild-type mice. Age (Dordr). 2012;34:1225-37 pubmed
Sackmann Sala L, Berryman D, Munn R, Lubbers E, Kopchick J. Heterogeneity among white adipose tissue depots in male C57BL/6J mice. Obesity (Silver Spring). 2012;20:101-11 pubmed publisher
Schweitzer G, Castorena C, Hamada T, Funai K, Arias E, Cartee G. The B2 receptor of bradykinin is not essential for the post-exercise increase in glucose uptake by insulin-stimulated mouse skeletal muscle. Physiol Res. 2011;60:511-9 pubmed
Hecker P, O Shea K, Galvao T, Brown B, Stanley W. Role of adiponectin in the development of high fat diet-induced metabolic abnormalities in mice. Horm Metab Res. 2011;43:100-5 pubmed publisher
Glier M, Pissios P, Babich S, MacDonald M, Hayden M, Maratos Flier E, et al. The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone. Peptides. 2010;31:123-9 pubmed publisher
Warden C, Fisler J, Espinal G, Graham J, Havel P, Perroud B. Maternal influence of prolyl endopeptidase on fat mass of adult progeny. Int J Obes (Lond). 2009;33:1013-22 pubmed publisher
product information
Catalog Number :
80-INSMSU-E01
Product Name :
Mouse Ultrasensitive Insulin ELISA
List Price :
399.00 USD
Description :
The Mouse Ultrasensitive Insulin ELISA quantifies the concentration of insulin protein products in mouse I and mouse II proinsulin genes from as little as 5 µL of serum or plasma sample. For Research Use Only. Not for Use in Diagnostic Procedures. Only 5 µL of sample required for tail snips Dynamic range of 0.18-6.9 ng/mL Superior sensitivity of 0.115 ng/mL Only 25 µL of sample required for hypoinsulinemic samples Dynamic range of 0.025-1.25 ng/mL Superior sensitivity of 0.019 ng/mL
Therapeutic Areas :
Diabetes & Obesity
Species :
Mouse
Sample Types :
Plasma, Serum
Size :
96 Wells
Regulatory Status :
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution :
Available Worldwide
Applications :
Immunoassays
Sample Size :
5 µL
Range :
0.025 - 6.9 ng/mL
Sensitivity :
0.115 ng/mL (5 µL), 0.019 ng/mL (25 µL)
Incubation Time :
2hr 30min
more info or order :
company information
ALPCO
26G Keewaydin Drive
Salem, NH 03079
email@alpco.com
http://www.alpco.com
1-603-893-8914
headquarters: USA
ALPCO was founded in 1990 as an importer and distributor of high quality research immunoassay kits. Since that time, their primary goals have been to offer a diverse line of assays that appeal to their broad customer base while also providing exceptional customer service and product support.