This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Thioredoxin-2 / TXN2 Protein, His Tag
catalog :
TX2-H5141
quantity :
100 ug, 1 mg
price :
198 USD, 980 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
TX2-H5141
product name :
Human Thioredoxin-2 / TXN2 Protein, His Tag
quantity :
100 ug, 1 mg
price :
198 USD, 980 USD
quantity & price :
$198/100ug,$980/1mg (500ug × 2)
target :
Thioredoxin-2
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human Thioredoxin-2, His Tag (TX2-H5141) is expressed from E.coli cells. It contains AA Thr 60 - Gly 166 (Accession # AAH13726).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human Thioredoxin-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Thioredoxin-2 (TXN2),a member of the thioredoxin family,is also known as mitochondrial (MTRX or Mt-Trx) and TRX2.TXN2 have two important domains: Redox-active center and Transit peptide. TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Also, TXN2 could be involved in the resistance to anti-tumor agents. TNX2 possesses a dithiol-reducing activity as well.
References :
(1) Chen Y., et al., 2002, J. Biol. Chem. 277:33242-33248.
(2) Damdimopoulos A.E., et al., 2002, J. Biol. Chem. 277:33249-33257.
(3) Smeets A., et al., 2005, Protein Sci. 14:2610-2621.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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