This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human TRAIL R4 / TNFRSF10D Protein, Fc Tag
catalog :
TR4-H5256
quantity :
200 ug, 1 mg
price :
290 USD, 1100 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
TR4-H5256
product name :
Human TRAIL R4 / TNFRSF10D Protein, Fc Tag
quantity :
200 ug, 1 mg
price :
290 USD, 1100 USD
quantity & price :
$290/200ug,$1100/1mg (500ug × 2)
target :
TRAIL R4
host species :
Human
By Tag :
Fc Tag
Research :
For Research Use Only
Source :
Human TRAIL R4, Fc Tag (TR4-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 56 - His 211 (Accession # NP_003831).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human TRAIL R4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) is also known as Decoy receptor 2 (DcR2), TNF-related apoptosis-inducing ligand receptor 4 (TRAIL receptor 4 or TRAIL-R4), CD264,which is the single-pass type I membrane protein. TNFRSF10D is receptor for the cytotoxic ligand TRAIL, which contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis.
References :
(1) Degli-Esposti M.A., et al., 1997, Immunity 7:813-820.
(2) Marsters S.A., et al, 1997, Curr. Biol. 7:1003-1006.
(3) Pan G., et al., 1998, FEBS Lett. 424:41-45.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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