This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human S100A1 Protein, His Tag
catalog :
S11-H5124
quantity :
100 ug, 1 mg
price :
300 USD, 1980 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
S11-H5124
product name :
Human S100A1 Protein, His Tag
quantity :
100 ug, 1 mg
price :
300 USD, 1980 USD
quantity & price :
$300/100ug,$1980/1mg (500ug × 2)
target :
S100A1
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human S100A1, His Tag (S11-H5124) is expressed from E.coli cells. It contains AA Met 1 - Ser 94 (Accession # AAH14392).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human S100A1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Protein S100-A1 / S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. S100-A1 can weakly bind calcium but bind zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
References :
(1) Engelkamp D., et al., 1992, Biochemistry 31:10258-10264.
(2) Wang G., et al., 2004, Biochem. J. 382:375-383.
(3) Yamaguchi F., 2012, J. Biol. Chem. 287:13787-13798.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
questions and comments