This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Cyclophilin B / PPIB Protein, His Tag
catalog :
PPB-H5229
quantity :
100 ug, 1 mg
price :
240 USD, 1400 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
PPB-H5229
product name :
Human Cyclophilin B / PPIB Protein, His Tag
quantity :
100 ug, 1 mg
price :
240 USD, 1400 USD
quantity & price :
$240/100ug,$1400/1mg (250ug × 4)
target :
Cyclophilin B
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human PPIB, His Tag (PPB-H5229) is expressed from human 293 cells (HEK293). It contains AA Asp 34 - Ala 212 (Accession # NP_000933).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human PPIB, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Peptidyl-prolyl cis-trans isomerase B (PPIB or PPIase B) is also known as Cyclophilin B (CYPB), Rotamase B, S-cyclophilin (SCYLP), is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum, which belongs to the cyclophilin-type PPIase family and PPIase B subfamily. PPIB / CYPB contains one PPIase cyclophilin-type domain. PPIases accelerate the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
References :
(1) Arber S., et al, 1992, J. Cell Biol. 116:113-125.
(2) Chi A., et al., 2006, J. Proteome Res. 5:3135-3144.
(3) Zhang, Jianying, et al., 2003, J. Biol. Chem. (United States) 278 (9): 7459–68.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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