This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Myocilin / MYOC Protein, His Tag
catalog :
MYC-H5222
quantity :
50 ug, 1 mg
price :
310 USD, 1980 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
MYC-H5222
product name :
Human Myocilin / MYOC Protein, His Tag
quantity :
50 ug, 1 mg
price :
310 USD, 1980 USD
quantity & price :
$310/50ug,$1980/1mg
target :
Myocilin
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human Myocilin, His Tag (MYC-H5222) is expressed from human 293 cells (HEK293). It contains AA Arg 33 - Met 504 (Accession # NP_000252).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human Myocilin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Myocilin, trabecular meshwork inducible glucocorticoid response is also known as MYOC, GLC1A, GPOA, JOAG, JOAG1, TIGR. Myocilin / MYOC contains one olfactomedin-like domain. Myocilin is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
References :
(1) Young H. Kwon., et al., 2009, N Engl J Med, 360:1113-24. (2) Torrado, Mario., et al., 2002, Hum. Mol. Genet. (England) 11 (11): 1291–301.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.