This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human IL-17 RC Protein, Fc Tag
catalog :
ILC-H5255
quantity :
1 mg, 100 ug
price :
1980 USD, 300 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
ILC-H5255
product name :
Human IL-17 RC Protein, Fc Tag
quantity :
1 mg, 100 ug
price :
1980 USD, 300 USD
quantity & price :
$300/100ug,$1980/1mg
target :
IL-17 RC
host species :
Human
By Tag :
Fc Tag
Research :
For Research Use Only
Source :
Human IL-17 RC, Fc Tag (ILC-H5255) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Arg 467 (Accession # NP_703190.2).
SDS-PAGE Remark(R&NR) :
Human IL-17 RC, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than .
Formulation :
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.
References :
(1) Wright JF. J Immunol. 2008 Aug 15;181(4):2799-805.
(2) Toy D. J Immunol. 2006 Jul 1;177(1):36-9.
(3) Kuestner RE. J Immunol. 2007 Oct 15;179(8):5462-73.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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