This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human IDH1 Protein, His Tag
catalog :
ID1-H5120
quantity :
50 ug, 1 mg
price :
250 USD, 1600 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
ID1-H5120
product name :
Human IDH1 Protein, His Tag
quantity :
50 ug, 1 mg
price :
250 USD, 1600 USD
quantity & price :
$250/50ug,$1600/1mg (500ug × 2)
target :
IDH1
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human IDH1, His Tag (ID1-H5120) is expressed from E.coli cells. It contains AA Met 1 - Leu 414 (Accession # NP_005887).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human IDH1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, 1 mM DTT, pH7.5. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Isocitrate dehydrogenase 1 (IDH1) is also known as Cytosolic NADP-isocitrate dehydrogenase (NADP(+)-specific ICDH), Oxalosuccinate decarboxylase and PICD, which is one of the Isocitrate dehydrogenases that can catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD+ as the electron acceptor and the other NADP+. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
References :
(1) Choudhary C., et al., 2009, Science 325:834-840.
(2) Xu X., et al., 2004, J. Biol. Chem. 279:33946-33957.
(3) Dang L., et al., 2009, Nature 462:739-744.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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