This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human ICAM-2 / CD102 Protein, His Tag
catalog :
IC2-H5220
quantity :
100 ug, 1 mg
price :
290 USD, 1600 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
IC2-H5220
product name :
Human ICAM-2 / CD102 Protein, His Tag
quantity :
100 ug, 1 mg
price :
290 USD, 1600 USD
quantity & price :
$290/100ug,$1600/1mg (500ug × 2)
target :
ICAM-2
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human ICAM-2, His Tag (IC2-H5220) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Gln 223 (Accession # NP_000864).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human ICAM-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
References :
(1) Xu G., et al., 2009, Proc. Natl. Acad. Sci. U.S.A. 106:19310-19315. (2) Liu T., et al., 2005, J. Proteome Res. 4:2070-2080. (3) Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.