This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human EphA7 Protein, His Tag
catalog :
EP7-H5221
quantity :
100 ug, 1 mg
price :
250 USD, 1440 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
EP7-H5221
product name :
Human EphA7 Protein, His Tag
quantity :
100 ug, 1 mg
price :
250 USD, 1440 USD
quantity & price :
$250/100ug,$1440/1mg (500ug × 2)
target :
EphA7
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human EphA7, His Tag (EP7-H5221) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ile 556 (Accession # AAI26126).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>98% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human EphA7, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Ephrin type-A receptor 7 (EPHA7) is also known as EPH homology kinase 3 (EHK3), EPH-like kinase 11 (HEK11), which belongs to the protein kinase superfamily or tyr protein kinase family or ephrin receptor subfamily. EPHA7 / EHK3 contains 1 Eph LBD (Eph ligand-binding) domain, 2 fibronectin type-III domains, 1 protein kinase domain, 1 SAM (sterile alpha motif) domain. EHK-3 / EPHA7 is widely expressed. The catalytic activity of EPHA7 / EHK3 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
References :
(1) Nakanishi H., et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104:14442-14447.
(2) Tsuboi M., et al., 2010, Int. J. Oncol. 36:635-640.
(3) Eph nomenclature committee, 1997, Cell 90:403-404.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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