This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Cystatin SN / CST1 Protein, His Tag
catalog :
CS1-H5225
quantity :
20 ug, 1 mg
price :
290 USD, 2000 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
CS1-H5225
product name :
Human Cystatin SN / CST1 Protein, His Tag
quantity :
20 ug, 1 mg
price :
290 USD, 2000 USD
quantity & price :
$290/20ug,$2000/1mg (500ug × 2)
target :
Cystatin SN
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human Cystatin SN, His Tag (CS1-H5225) is expressed from human 293 cells (HEK293). It contains AA Trp 21 - Ser 141 (Accession # AAH21225).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human Cystatin SN, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH6.0. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Cystatin-1 (CST1) is also known as Cystatin-SN, Cystain-SA-I, Salivary cystatin-SA-1, which is secreted protein and belongs to the cystatin family. Cystatin-1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and also expressed in saliva, tears, urine and seminal fluid. Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
References :
(1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824. (2) Ryan C.M., et al., 2010, J. Am. Soc. Mass Spectrom. 21:908-917.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.