This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Choline Kinase beta / CKB type Protein, His Tag
catalog :
CKB-H5143
quantity :
500 ug
price :
340 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
CKB-H5143
product name :
Human Choline Kinase beta / CKB type Protein, His Tag
quantity :
500 ug
price :
340 USD
quantity & price :
$340/500ug
target :
Choline Kinase beta
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human CKB, His Tag (CKB-H5143) is expressed from E.coli cells. It contains AA Pro 2 - Lys 381 (Accession # AAH19259).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human CKB, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Creatine kinase B-type (CKB) is also known as Creatine kinase B chain, B-CK and CKBB. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Furthermore, ectopic expression of the CKB in red cells and platelets is a rare, benign anomaly detected during a newborn screening program for Duchenne muscular dystrophy.
References :
(1) Daouk G.H., et al., 1988, J. Biol. Chem. 263:2442-2446. (2) Olsen J.V., et al., 2010, Sci. Signal. 3:RA3-RA3.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.