This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human CD300a / LMIR1 Protein, Fc Tag
catalog :
CDA-H5257
quantity :
100 ug, 1 mg
price :
250 USD, 1440 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
CDA-H5257
product name :
Human CD300a / LMIR1 Protein, Fc Tag
quantity :
100 ug, 1 mg
price :
250 USD, 1440 USD
quantity & price :
$250/100ug,$1440/1mg (500ug × 2)
target :
CD300a
host species :
Human
By Tag :
Fc Tag
Research :
For Research Use Only
Source :
Human CD300a, Fc Tag (CDA-H5257) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Gln 178 (Accession # AAH32352).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human CD300a, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
CD300 antigen-like family member A (CD300A) is also known as CMRF35-like molecule 8 (CLM-8), CMRF-35-H9, CMRF35-H, Immunoglobulin superfamily member 12 (IGSF12), NK inhibitory receptor, LMIR1, which belongs to the CD300 family. CD300A contains one Ig-like V-type (immunoglobulin-like) domain. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is a inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
References :
(1) Green B.J., et al., 1998, Int. Immunol. 10:891-899. (2) Clark G.J., et al., 2000, Tissue Antigens 55:101-109. (3) Bachelet I., et al., 2005, J. Immunol. 175:7989-7995.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.