This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human Carbonic Anhydrase XIV / CA14 Protein, His Tag
catalog :
CA4-H5227
quantity :
50 ug, 1 mg
price :
290 USD, 1800 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
CA4-H5227
product name :
Human Carbonic Anhydrase XIV / CA14 Protein, His Tag
quantity :
50 ug, 1 mg
price :
290 USD, 1800 USD
quantity & price :
$290/50ug,$1800/1mg (250ug × 4)
target :
Carbonic Anhydrase XIV
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human Carbonic Anhydrase XIV, His Tag (CA4-H5227) is expressed from human 293 cells (HEK293). It contains AA Ala 16 - Met 290 (Accession # AAH34412).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>95% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human Carbonic Anhydrase XIV, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Carbonic anhydrase XIV (CA14),a member of the alpha-carbonic anhydrase family, is also known as carbonate dehydratase XIV, which is a single-pass type I membrane protein. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA14 shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. As for tissue specificity,CA14 is high expressed in all parts of the central nervous system and lower expressed in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
References :
(1) Temperini C., et al., 2006, Chemistry 12:7057-7066. (2) Di Fiore A., et al., 2009, Proteins 74:164-175. (3) Alterio V., et al., 2014, Biopolymers 101:769-778.
company information
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
info@acrobiosystems.com
http://www.acrobiosystems.com
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.