This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ACROBiosystems
product type :
protein
product name :
Human B3GAT3 Protein, His Tag
catalog :
B33-H5141
quantity :
100 ug, 1 mg
price :
250 USD, 1300 USD
product information
company name :
ACROBiosystems
product type :
Protein
catalog :
B33-H5141
product name :
Human B3GAT3 Protein, His Tag
quantity :
100 ug, 1 mg
price :
250 USD, 1300 USD
quantity & price :
$250/100ug,$1300/1mg (500ug × 2)
target :
B3GAT3
host species :
Human
By Tag :
His Tag
Research :
For Research Use Only
Source :
Human B3GAT3, His Tag (B33-H5141) is expressed from E.coli cells. It contains AA Glu 72 - Val 335 (Accession # AAH07906).
Endotoxin :
Less than 1.0 EU per μg by the LAL method.
Purity :
>92% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human B3GAT3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Reconstitution :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
● -20°C to -70°C for 12 months in lyophilized state;
● -70℃ for 3 months under sterile conditions after reconstitution.
Background :
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3), a member of the glycosyltransferase 43 family, is also known as beta-1,3-glucuronyltransferase 3, glucuronosyltransferase I (GlcAT-I) and UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase (GlcUAT-I). B3GAT3 plays a role in glycosaminoglycans biosynthesis and be involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. B3GAT3 can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Furthermore,B3GAT3 shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc.
References :
(1) Kitagawa H., et al., 1998, J. Biol. Chem. 273:6615-6618.
(2) Pedersen L.C., et al., 2000, J. Biol. Chem. 275:34580-34585.
(3) Tone Y., et al., 2008, J. Biol. Chem. 283:16801-16807.
company information
ACROBiosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics. The company employs an application oriented development strategy, with a particular focus on product design, quality control and solution based support. Our products and services enable anyone in the field of drug development to have a more intuitive and streamlined process. We have multiple offices and branches in North America, Europe, and Asia, and we are proud of serving customers from over 50 countries.
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