Changes in Biomedical Research Reagent/Instrument Companies
Synatom Research, Princeton, New Jersey, United States
DOI
//dx.doi.org/10.13070/mm.en.4.916
Date
last modified : 2024-07-10; original version : 2014-06-29
Cite as
MATER METHODS 2014;4:916
Abstract
A select list of changes in reagent/instrument companies and major brands over the years. It helps Labome visitors find correct reagent/instrument resources.
2024
- July 9, Certara to acquire Chemaxon, a developer of software products for chemical structure drawing, property prediction, search, and analysis.
- July 9, Illumina acquires Fluent BioSciences, developer of an emerging and highly differentiated single-cell technology.
- May 23, MilliporeSigma to acquire Mirus Bio for $600 million.
2023
- October, Thermo Fisher Scientific (NYSE: TMO) acquired Olink for $3.1 billions.
- August, Danaher (NYSE: DHR) acquire Abcam plc (NASDAQ: ABCM) for $5.7 billions.
- May, PerkinElmer rebranded diagnostics and life sciences business as Revvity.
- March, PerkinElmer sold off its applied science, food and enterprise services businesses to private equity firm New Mountain Capital for 2.45 billions.
- March, Sartorius bought viral vector specialist French company Polyplus for 2.6 billions.
- February, Donaldson bought reagent firm Isolere Bio.
- February, Cytek Biosciences acquired flow cytometry and imaging business from DiaSorin.
- January, Charles River Laboratories International (NYSE: CRL) acquired SAMDI Tech, a leading provider of high-quality, label-free high-throughput screening (HTS) solutions for drug discovery research.
2022
- December, Polyplus acquired Xpress Biologics.
- September, Danaher merged Cytiva and Pall.
- March, Fortis Life Sciences acquired Abcore.
- February, Rockland Immunochemicals acquired antibodies-online GmbH, received investment from BroadOak Capital Partners.
- January, Fluidigm (NASDAQ:FLDM) was re-branded to Standard BioTools Inc (NASDAQ:LAB).
- January, Thermo Fisher Scientific acquired PeproTech, a manufacturer of recombinant proteins for 1.85 billions.
2021
- November, Biocompare acquired Chromocyte.
- November, Cytek Biosciences (Nasdaq: CTKB) acquired the cell analysis business of Tonbo Biosciences.
- October, Fortis Life Sciences acquired Empirical Bioscience.
- September, Roche acquired TIB Molbiol.
- August, Abcam acquired BioVision for $340 million.
- July, Atlas Antibodies acquired evitria.
- July, PerkinElmer bought BioLegend for $5.25 billion.
- March, Bio-Techne Corporation (NASDAQ: TECH) acquired Asuragen, Inc. for initial consideration of $215 million in cash plus contingent consideration of up to $105 million upon the achievement of certain future milestones.
2020
- December, LifeSpan BioSciences (LSBio) acquired Absolute Antibody and its sister company Kerafast.
- November, Fortis Life Sciences acquired Bethyl Laboratories.
- October, Calibre Scientific acquired Dianova GmbH, a life science manufacturer and distributor, and integrated it with BIOZOL Diagnostica GmbH.
- October, Proteintech Group acquired ChromoTek.
- June, the Finnish supplier of IVD products, Medix Biochemica, bought EastCoast Bio.
- January, Abcam purchased Applied StemCell's gene editing platform and oncology product portfolio.
2019
- October, Edgewater Capital Partners, a sector-focused private equity firm, acquired Haematologic Technologies.
- October, MilliporeSigma acquired FloDesign Sonics, of Wilbraham, Massachusetts, developer of an acoustic cell processing platform.
- July, LifeSpan BioSciences acquired Everest Biotech.
- July, Quanterix acquired UmanDiagnostics for $22.5M.
- June, Beckman Coulter Life Sciences acquired Cytobank, a privately held company based in Santa Clara, California.
- June, Bio-Techne Corporation acquired all of the stock of B-MoGen Biotechnologies, a gene-editing company spun out from the University of Minnesota in 2015.
- February, Danaher Corporation (NYSE: DHR) acquired the Biopharma business of GE Life Sciences for $21.4 billion. Danaher's Life Sciences segment has Pall, Beckman Coulter Life Sciences, SCIEX, Leica Microsystems, Molecular Devices, Phenomenex, and IDT businesses.
- February, Danaher acquired the biopharma business of General Electric Life Sciences for $21.4 billion, renaming the business later as Cytiva. Cytiva includes ÄKTA (chromatography systems), Amersham (imaging systems), HyClone (cell culture and fermentation process products), MabSelect (a BioProcess protein A resin), Whatman (lab supplies and consumables such as filters, devices, and membranes).
- February, Charles River acquired Citoxlab for 510 million USD.
- January, PHC Holdings Corporation acquired Thermo Fisher's anatomic pathology business for 1.14 billion USD.
- January, Abcam acquired Calico Biolabs.
- January, Beckman Coulter Life Sciences acquired Labcyte, an acoustic liquid handling company based in San Jose, California.
2018
- December, 10x Genomics acquired Spatial Transcriptomics.
- November, Thermo Fisher subsidiary, Affymetrix, acquired Panomics, a privately held Fremont, California-based company that offers a powerful suite of assay products for a wide variety of low to mid-plex genetic, protein and cellular analysis applications.
- November, DNA sequencing company Illumina tried to buy the smaller rival Pacific Biosciences for $1.2 billion; however the deal was terminated due to the possibility of a lengthy regulatory approval process in Jan 2020.
- November, Precision BioLogic acquired Affinity Biologicals, a manufacturer of reagents and kits used in hemostasis and thrombosis research and diagnostics.
- October, Lonza acquired a controlling stake in Octane Biotech.
- September, Thompson Street Capital Partners acquires LifeSpan Biosciences.
- September, Brooks Automation acquired Genewiz Group for $450 million.
- September, Thermo Fisher Scientific acquired the Advanced Bioprocessing Business division from BD.
- August, 10x Genomics acquired Epinomics.
- June, Janel Corp purchased Antibodies Inc.
- June, Exalpha Biologicals, Inc. acquired chicken antibody company Gallus Immunotech Inc.
- June, FUJIFILM Corporation acquired Irvine Scientific Sales Company, Inc. (ISUS) and IS JAPAN CO.,LTD. (ISJ), leading companies in cell culture media for about US$800 million.
- May, CalibreScientific acquired BIOZOL Diagnostica Vertrieb GmbH, an independent distributor of life science products across Germany. CalibreScientific has acquired Anatrace, Edge Biosystems, Microlytic, ion chromatography business from Transgenomics, Molecular Dimensions, Alpha-Tec Systems, Protein Ark, and BioServUK since 2013.
- May, Illumina bought Edico Genome, an informatics company specializing in genome sequencing in San Diego, for $100M.
- May, Janel Corp purchased Aves Lab.
- May, Thomas Scientific acquired E&K Scientific.
- April, Proteintech acquired HumanZyme, a manufacturer of recombinant human proteins.
- March, Integrated DNA Technologies ("IDT") was purchased by Danaher Corporation, a public company with the NYSE ticker: DHR, which also purchased several life science companies over the years: Beckman Coulter Life Sciences, Leica Microsystems, Molecular Devices, Pall, Phenomenex, and SCIEX.
- March, BioLogo was acquired by Nordic-MUbio.
- February, Abcam became the exclusive distributor of Spring Bioscience recombinant rabbit monoclonal SP clones.
- February, LGC, a UK company, owned by funds affiliated with KKR, purchased Lucigen, a Middleton, WI-based vendor of life sciences research tools. LGC provides testing services, reference materials, and ancillary products to organizations in the diagnostic and drug development industries, among others. Lucigen is a spinout of Promega in 1998.
- February, Absolute Antibody, a recombinant antibody technology company, and Kerafast, a provider of researcher-generated reagents merged.
- January, Maravai LifeSciences acquired Glen Research Corporation.
- January, BIO-TECHNE acquired Atlanta Biologicals Inc.
- January, Charles River Laboratories acquired KWS BioTest for 20 million USD.
2017
- December, Japanese JSR Corporation purchased Crown Bioscience.
- September, Bio-Techne acquired Trevigen.
- August, Massachusetts-based Nuclea Biotechnologies filed for Chapter 7 bankruptcy.
- August, ImmunoPrecise Antibodies acquired Utrecht, The Netherlands-based U-Protein Express for 6.83 million Euros
- July, Horizon Discovery acquired Dharmacon from GE for 85 million USD.
- June, Japanese JSR Corporation purchased Switzerland-based Selexis SA.
- June, a Chinese company Boai NKY Pharmaceuticals acquired U.S. firm BioVision for up to $290 mln. BioVision's revenues for 2015 and 2016 are 18 million and 21 million, with profits of 6 million and 11 million, respectively.
- May, Thermo Fisher bought Patheon, Dutch drug ingredients maker, in a $5.2 billion deal.
- April, Japan’s Fujifilm acquired Wako Pure Chemical Industries for $1.3 billion.
- April, Sartorius acquired Essen BioScience for $320 million .
- February, Aviva Systems Biology acquired GenWay Biotech.
2016
- December, Maravai LifeSciences acquired the commercial assets of Solulink Incorporated, which were integrated into its TriLink BioTechnologies.
- October, Maravai LifeSciences acquired TriLink Biotechnologies and Cygnus Technologies.
- June, Qiagen completed Exiqon tender offer for about 103 million USD.
- May, Thermo Fisher Scientific acquired FEI Company, which was formed by the 1997 merger between FEI and Philips Electron Optics and the 1999 acquisition of Micrion.
- April, Maravai acquired Vector Laboratories.
- January, Qiagen acquired Mo Bio.
- January, Thermo Fisher Scientific acquired Affymetrix including eBioscience, for $1.3 billion.
2015
- November, OriGene acquired Acris Antibodies.
- November, Abcam acquired AxioMx for up to 45 million USD.
- September, Thermo Fisher Scientific acquired Alfa Aesar.
- August, Roche acquired Kapa Biosystems.
- May, Danaher acquired Pall for about $13.8 billion.
- January, ABCAM acquired Firefly BioWorks for £18.5m ($28.0m).
2014
- October, REPROCELL acquired the business of iPS cell business department of Stemgent.
- October, Sigma acquired Cell Marque Corporation.
- September, BioLegend acquired the Antibody Products business unit from Covance.
- September, EMD Millipore/Merck Group acquired Sigma-Aldrich.
- July, Bio-Techne, with brands: R & D Systems, Tocris, and Boston Biochem, acquired Novus Biologicals.
- June, Bio-Techne, with brands: R & D Systems, Tocris, and Boston Biochem, acquired ProteinSimple for $300 million.
- June, Malvern Instruments acquired MicroCal business from GE Healthcare Life Sciences.
- January, GE Healthcare acquired HyClone cell culture media, sera and process liquids; Dharmacon RNAi gene modulation tools; and Sera-Mag magnetic beads businesses from Thermo Fisher.
- January, Fluidigm acquired DVS Sciences for $207.5 million.
2013
- October, IMGENEX became part of Novus Biologicals.
- October, Illumina acquired NextBio.
- September, Nuclea Biotechnologies acquired Wilex' U.S. subsidiary (Oncogene Science).
- Thermo Fisher bought Life Technologies for $13.6 billion.
- ACTGen merged into MBL.
- September, Alfa Aesar acquired Biomedical Technologies, Inc. of Stoughton, Massachusetts.
- April, QIAGEN acquired Ingenuity Systems.
2012
- December, Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) bought AbD Serotec, a division of MorphoSys AG, for 53 million euros in cash.
- December, Rockland Immunochemicals Inc. acquired TrueBlot® IP/Western blot product line from eBioscience, Inc., an Affymetrix (NASDAQ:AFFX) company.
- October, Corning acquired the majority of BD’s (Becton Dickinson and Company) Discovery Labware business, including brands: AccuCell™, Advantage®, BD branded ECM products, BioCoat, Cell-Tak™, Epranex®, Express®, Falcon FluoroBlok™, Falcon, Gentest Supermix®, Gentest™, Gold Seal®, Hepatolink®, ITS®, Matrigel®, Mito+™, Natrix®, Nu-Serum®, Optilux®, Primaria™, PureCoat™, Sero-Liner®, Supermix®, Supersomes®, UltraPool™ .
- August, Merck KGaA Acquires Cell Culture Media Specialist Biochrom AG.
- July, Thermo Fisher bought One Lambda for $925 million.
- May, Merck acquired 100% of the shares in CellASIC Corp., Hayward, CA, USA, and then merged the company with EMD Millipore Corp.
- May, Agilent acquired Dako for 2.2 billion USD.
- March, Abcam PLC bought Epitomics International Inc for $170.0 million in cash and shares.
- March, OriGene Technologies acquired Beijing Zhongshan Golden Bridge Biotech.
2011
- Fujifilm bought SonoSite.
- Corning acquired Mediatech, with the Cellgro media.
- Pall Corp. acquiree life science company ForteBio.
- November 30, Affymetrix, Inc., (NASDAQ: AFFX) acquired eBioscience, Inc. for $330 million in cash.
- October 13, WuXi PharmaTech (Cayman) Inc. (NYSE: WX) acquired Abgent.
- September, Abcam acquired Ascent Scientific, a specialist provider of biochemicals.
- August, EMD Millipore, the Billerica, MA-based subsidiary of German pharmaceutical and chemical giant Merck KGaA, acquired Seattle-based Amnis.
- July, Roche acquired mtm laboratories AG.
- April, R&D Systems and RDSE acquired 100% ownership of Tocris Holdings Limited and subsidiaries (Tocris).
- April, R&D Systems acquired the assets of Boston Biochem, Inc.
2010 and earlier
- November 2010, WILEX acquired Oncogene Science assets from Siemens Healthcare Diagnostics, including serum HER-2/neu ELISA kit.
- Fujirebio purchased Innogenetics in 2010.
- Eurogentec purchased Anaspec in 2009, and was purchased by Kaneka Group.
- Sony purchased iCyt Mission Technology, a manufacturer of flow cytometers.
- Thermo Fisher Scientific acquires proteomics workflow solution provider, Proxeon.
- Life Technologies bought GeneART.
- SonoSite acquired Visualsonics.
- Life Technologies acquired Arcturus, a provider of complete Systems for Microgenomics®, Arcturus® Laser Capture Microdissection products, PicoPure RNA and DNA isolation kits.
- Lonza acquired cell research company Amaxa, including its Nucleofector systems and reagents.
- AB SCIEX acquired Eksigent liquid chromatography business.
- Waters purchased mass spectrometry maker Micromass.
- Eppendorf AG, Hamburg, acquired New Brunswick Scientific.
- QIAGEN acquired SABiosciences in 2009.
- GE Healthcare acquired Biacore.
- Millipore acquired Guava Technologies.
- Corning Incorporated acquired Axygen BioScience.
- Sekisui Chemical Co., Ltd. acquired 100% of the shares of American Diagnostica in 2009.
- Whatman Plc was acquired in 2008 by GE Healthcare.
- QIAGEN acquired Corbett life science, an Australian developer, manufacturer, and distributor of life sciences instrumentation, best known for having developed the world's first rotary real-time PCR cycler system -- the Rotor-Gene in 2008.
- Daiichi Sankyo transferred all Daiichi Fine Chemical Shares to Kyowa Hakko in 2007.
- Agilent bought Stratagene for $246M in 2007.
- Cortex BioChem of San Leandro, California was purchased by Trinity Biotech in 2007.
- Cappel was purchased by MP Bio.
- Millipore Corporation (MIL) bought Serologicals Corporation (SERO) for $1.4 billion in 2006.
- Clontech was purchased by Takara Bio in 2005.
- Serologicals Corporation acquired AltaGen Biosciences and Sierra BioSource subsidiary in 2004.
- Fisher Scientific acquired Perbio Science AB, a consumable supplier to life-science and biotechnology industries in 2003.
- The Techne Corporation (Bio-Techne) bought the Genzyme Corporation's research-products unit for about $65.5 million in cash, stock, and royalties in 1998.
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