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- citations: 109
Cat.No. 1213 - PD 98059 C16H13NO3 CAS No. 167869-21-8
quantity: 1 mg (also 10 mg, 50 mg)
price: 100 USD
to the supplier - citations: 1
Alomone Labs PD 98059 inhibits P42/44 MAPK (ERK) phosphorylation via MEK in C6 glioma cells. - Cells were grown to 70% confluence and serum starved for 1.5 h. The cells were then incubated for 2 h with various concentrations ofPD 98059(#P-260) and stimulated with 7 ng/ml PDGF-AA. Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-P42/44 (upper panel) and with anti-P42/44 (lower panel) antibodies. Inhibition of P42/44 phosphorylation by PD 98059 was dose-dependent.
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gene information - human MKK3
- synonym:MAPKK3; MEK3; MKK3; PRKMK3; SAPKK-2; SAPKK2
- description:mitogen-activated protein kinase kinase 3
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