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- citations: 123
Cat.No. 1202 - SB 203580 C21H16FN3OS CAS No. 152121-47-6
quantity: 1 mg (also 10 mg, 50 mg)
price: 155 USD
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Alomone Labs SB 203580 inhibits the phosphorylation of Elk1 and Atf2 via p38 in 3T3-L1 cells. - Cells were grown to 70% confluence and serum starved for 3 h. The cells were then incubated for 2 h with various concentrations ofSB 203580(#S-370) and stimulated with 5 MAnisomycin(#A-520). Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-p38 MAPK antip38 MAPK anti-phospho-Elk1 and anti-phospho-Atf2 as indicated. The phosphorylation of Elk1 and Atf2 decreased in a dose-dependent manner.
Alomone LabsQO-40enhances KCNQ2/KCNQ3heteromeric channels expressed inXenopusoocytes. - A. Time course of KCNQ2/KCNQ3 current enhancement by 40 and 100 MQO-40(#Q-265). Currents were elicited by application of voltage step from a holding potential of -100 mV to -60 mV (800 msec). B. Superimposed example traces of current responses before and during perfusion of 40 and 100 M QO-40 as indicated.
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gene information - human MAPK8IP2
- synonym:IB-2; IB2; JIP2; PRKM8IPL
- description:mitogen-activated protein kinase 8 interacting protein 2
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