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- citations: 24
Alomone Labs Margatoxininhibits KV1.3 currents expressed inXenopusoocytes. - A. Time course ofMargatoxin(#STM-325) action on Kv1.3 currents. Current amplitudes were plotted as a function of time. Membrane potential was held at ?100 mV and oocytes were stimulated by a 100 ms voltage ramp to +60 mV. 0.5 nM Margatoxin were perfused as indicated by the bar (green) at + 55 mV for 180 sec. B. Superimposed examples of KV1.3 channel current in the absence (control) and presence (green) of 0.5 nM Margatoxin (taken from the experiment in A).
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Alomone LabsCP 339818 hydrochlorideinhibits KV1.3 channels heterologously expressed inXenopusoocytes. - A. Time course of reversible current inhibition of KV1.3 current amplitude by 200 ?MCP 339818 hydrochloride(#C-115). Ramp stimulation; 100 ms from holding potential -100 mV to +20 mV delivered every 10 seconds. B. Superimposed current traces of control and inhibited current as indicated (taken from the experiment in A).
Peptide (C)RSGKYLATEWNTVSK corresponding to amino acid residues 36-50 of rat LPA1 receptor (AccessionP61794). Extracellular N-terminus.
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Expression of Neuregulin-1 in rat neocortex - Immunohistochemical staining of perfusion-fixed frozen rat brain sections using Anti-NRG1 (Neuregulin-1) (extracellular)Antibody (#ANR-111) (1:1000) followed by anti-rabbit-biotinylated antibody and streptavidin-Cy3 (red). Neuregulin-1 staining is strong in processes of various cell types (horizontal arrows) and less intense in neuron-shaped soma (vertical arrows). Nuclei are stained with DAPI (blue).
Alomone LabsADWX-1 inhibits KV1.3 currents heterologously expressed inXenopusoocytes. - A. Time course ofADWX-1(#STW-100) blocking action on KV1.3 currents. Membrane potential was held at -80 mV and cells were stimulated by a 100 ms voltage ramp to +40 mV. 1 nM ADWX-1 was perfused as indicated by the bar (green) at +35 mV. B. Superimposed examples of KV1.3 channel current in the absence (control) and presence (green) of 1 nM ADWX-1 (taken from the experiment in A).
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gene information - human Kv1.3
- synonym:HGK5; HLK3; HPCN3; HUKIII; KV1.3; MK3; PCN3
- description:potassium voltage-gated channel subfamily A member 3
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