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Alomone Labs HumanGFR?1-FcChimera inhibits GDNF-induced ERK1/2 MAPK and Akt phosphorylation in SH-SY5Y cells. - Cells were serum deprived for 2 hr and then stimulated for 10 min with 10 ng/mlRecombinant human GDNF protein(#G-240) (lane 2) 4 g/mlHumanGFR?1-Fc Chimera(#RPC-003) preincubated with 10 ng/ml Recombinant human GDNF protein for 90 min (lane 3). Control cells incubated without Recombinant human GDNF protein are shown in lane 1. Cell proteins were resolved by SDS-PAGE and detected with anti-phospho-Akt (A) or with anti-ERK1/2 MAPK (B).
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gene information - human GDNF
- synonym:ATF; ATF1; ATF2; HFB1-GDNF; HSCR3
- description:glial cell derived neurotrophic factor
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