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- domestic rabbit polyclonal
reactivity: Saccharomyces cerevisiae S288C
application: western blot, ELISA
Most modifiers mature by proteolytic processing from inactive precursors (a; amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked head-to-tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch.
quantity: 500 µg
price: 432.00 USD
to the supplier - domestic rabbit polyclonal
reactivity: Saccharomyces cerevisiae S288C
application: western blot, ELISA
gene information - Saccharomyces cerevisiae S288C URM1
- description:ubiquitin-related modifier URM1
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product type
- URM1 antibody
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