Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
- Lifespan Biosciences polyclonal rabbit anti-HIF-1beta antibody was used to affect immunoneutralization and perform western blot in order to study the effect of elevated HO-1 during brain stem death.
- Lifespan Biosciences anti-PROKR1 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway.
- Lifespan Biosciences anti-HADHB antibody was used to perform western blot in order to reveal how viperin facilitates the infectious process.
- LifeSpan BioSciences goat polyclonal NS3 antibody was used to perform western blot in order to develop a sensitive reporter system for screening compounds against hepatitis C virus (HCV).
- Lifespan Biosciences anti-IDH1 antibody was used to perform western blot in order to study the function of quiescent fibroblasts.
- Lifespan Biosciences rabbit anti-TRIM32 antibody (1:1000) was used in western blot in order to demonstrate that muscular dystrophy due to E3 ubiquitin ligase (TRIM32) mutations involves both neurogenic and myogenic characteristics.
- LifeSpan Biosciences anti-FPRL1 antibody (1:100) was used in flow cytometry in order to study the role of pro-inflammatory peptide LL-37 in the ovarian tumor progression
- Lifespan Biosciences P2X7 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds
- LifeSpan Biosciences rabbit anti-human BLT2 receptor antibody was used in immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
- LifeSpan Biosciences rabbit anti-human BLT1 receptor antibody was used in western blot and immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
- IHC-plus™ GPR68 / OGR1 Antibody (N-Terminus) LS-A3968
- MAPK14 / p38 Antibody (phospho-Thr180/Tyr182) LS-C212
- TLR3 Antibody (clone 40C1285.6) LS-C545
- IHC-plus™ PDE3A Antibody (N-Terminus) LS-A732
- HMG1 / HMGB1 Antibody (aa100-200) LS-C2691
- ATM Antibody (phospho-Ser1981, clone 10H11.E12) LS-C2763
- BUB1B / BubR1 Antibody (aa1-350, clone 8G1) LS-C2771
- SCP1 / SYCP1 Antibody (C-Terminus) LS-C2911
- VEGFA / VEGF Antibody (clone VG76e) LS-C2929
- BMF Antibody (clone 9G10) LS-C4126