type 2 diabetes mellitus
gene
reagent
sample publication
sample review
total:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 to the paper
Upstate Biotechnology anti-TCF-4 antibody was used in immunoprecipitation and western blotting to investigate the action mechanism of the growth inhibition induced by bis[2-(acylamino)phenyl] disulfide. more
total:1
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
ABGENT anti-GCK(N-term) polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm.
total:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-p15 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma.
total:10
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Santa Cruz Biotechnology HNF-4alpha antibdoy was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR more
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:3
Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts. 2008 to the paper
Calbiochem rabbit anti-IDE antibody was used in western blot in order to demonstrate that Sca-1 localizes to lipid microdomains in myogenic precursors and that it associates with a catalytically active intracellular messenger IDE more
total:1
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. 2006 to the paper
Santa Cruz Biotechnology goat affinity-purified polyclonal anti-MT2 antibody (sc-28453) were used in human placental tissue and placental choriocarcinoma cell lines, and which were used in western blot and immunocytochemistry, to study the expression and role of melatonin receptors in human placenta choriocarcinoma cell lines.
total:12
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-HNF4 alpha antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
- islet specific glucose 6 phosphatase catalytic subunit related protein antibody
- islet specific glucose 6 phosphatase catalytic subunit related protein gene knockdown
- islet specific glucose 6 phosphatase catalytic subunit related protein cDNA
- islet specific glucose 6 phosphatase catalytic subunit related protein protein
- islet specific glucose 6 phosphatase catalytic subunit related protein other
total:1
SPBP is a phosphoserine-specific repressor of estrogen receptor alpha. 2005 to the paper
Gramsch Laboratories rabbit polyclonal antiserum raised against recombinant protein His6-SPBP (1459-1615) was used in western blot to identify SPBP as a phosphoserine-specific repressor of estrogen receptor.
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
total:2
Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. 2009 to the paper
Santa Cruz goat anti-Q1 antibody was used to perform western blot in order to locate KCNE1 relative to KCNQ1 in the potassium channel. more
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:3
KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. 2005 to the paper
Transduction Laboratories anti-KLF11 antibody was used in ChIP assay to study that KLF11-mediated repression antagonizes Sp1/Sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. more
total:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-ACE was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:2
Host biomarkers and biological pathways that are associated with the expression of experimental cerebral malaria in mice. 2008 to the paper
Novus Biologicals anti-hemoglobin alpha1 antibody was used in western blot to identify novel host molecules in the brain that are affected in the course of the pathological manifestation of CM. more
total:3
Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 2005 to the paper
Santa Cruz Biotechnology Ucp2 antibody was used in western blot to study the molecular mechanisms in enhancing the resistance to infectious microorganisms by disrupting the uncoupling protein-2 gene. more
total:5
Expression of the receptor for advanced glycation end products in oligodendrocytes in response to oxidative stress. 2008 to the paper
Santa Cruz Biotechnology polyclonal goat anti-RAGE antibody was used in western blot and immunohistochemistry in order to study the role of RAGE in the pathogenesis of demyelinating disease more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
total:1
UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells. 2008 to the paper
Chemicon rabbit anti-UCP-3 antibody (AB-3046) was used in western blot and immunohistochemistry to study the distinct roles for UCP-2 and UCP-3 in regulating beta-cell function.
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:8
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Santa Cruz Pdx1 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:1
Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. 2008 to the paper
Covance Ahi1 antibody was used in western blot in order to study the pathogenesis of Joubert syndrome and the role of the Ahi1-Hap1 complex in early brain development
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:6
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Santa Cruz anti-NeuroD1 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more