t lymphocytes
gene
reagent
sample publication
sample review
interleukin 2
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
PDCD1
programmed cell death 1
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
Lck
LCK proto-oncogene, Src family tyrosine kinase
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
CD274
CD274 molecule
total:4
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend anti-B7-H1 antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
CD247
CD247 molecule
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CD45
protein tyrosine phosphatase receptor type C
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
CD3E
CD3e molecule
total:20
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
eBioscience anti-CD3 monoclonal antibody OKT3 was used to stimulate CD4+ T cell in order to study novel HIV-1 capture mechanism. more
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
FOXP3
forkhead box P3
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
SH2D1A
SH2 domain containing 1A
total:2
Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP. 2011 to the paper
Abnova anti-SAP mAb was used to perform intracellular flow cytometric analysis in order to identify SAP expression in the lymphocytes obtained from XLP patients. more
CTLA 4
cytotoxic T-lymphocyte associated protein 4
total:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 to the paper
Santa Cruz anti-CTLA-4 antibody was used to perform immunocytochemistry in order to reveal the reason why CTLA-4 can inhibit CD28 stimulation. more
NFATC2
nuclear factor of activated T cells 2
total:5
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Cell signaling rabbit anti-NFAT1 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
IFN-gamma
interferon gamma
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
IL-7
interleukin 7
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
HLA DQA1
major histocompatibility complex, class II, DQ alpha 1
total:4
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Biomedical Technologies anti-MHC antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
CXCR3
C-X-C motif chemokine receptor 3
total:11
A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. 2008 to the paper
R&D Systems monoclonal anti-CXCR3 was used to perform blocking or activating experiments in order to show that a computational-based peptidomics can be used to identify peptides inhibiting the proliferation and migration of endothelial cells systematically. more
CD28
CD28 molecule
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
PRKCQ
protein kinase C theta
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
CD4
CD4 molecule
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
ZAP 70
zeta chain of T cell receptor associated protein kinase 70
total:19
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate ZAP-70 antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more
Kv1.3
potassium voltage-gated channel subfamily A member 3
total:6
Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. 2008 to the paper
Sigma FLAG antibody (1:1000) was used to perform western blot in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta. more
SLP 76
lymphocyte cytosolic protein 2
total:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-SLP-76 (BLNK)(pY128) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CARMA1
caspase recruitment domain family member 11
total:2
The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. 2008 to the paper
Prosci anti-CARD11 antibody was used in western blot in order to demonstrate that CARD11 can recruit signaling cofactors independently of one another in a signal-inducible manner. more
IL7R
interleukin 7 receptor
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
TRG
T cell receptor gamma locus
total:2
Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation. 2009 to the paper
BD monoclonal anti-TCRgd antibody (clone:11F2) was used in flow cytometry to study the association of girls homozygous for an IL-2-inducible T cell kinase mutation with protein deficiency develop fatal EBV-associated lymphoproliferation. more
TNFSF9
TNF superfamily member 9
total:4
Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity. 2005 to the paper
Santa Cruz Biotechnology goat anti-4-1BBL polyclonal Ab was used in western blot to detect WT AviTag-4-1BBL produced in E. coli and FLAG-4-1BBL produced in human HEK293 cells, as well as WT AviTag 4-1BBL produced in S2 Drosophila cells more