snRNP Assembly
gene
reagent
sample publication
sample review
total:3
Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. 2006 to the paper
BD Transduction Laboratories anti-pICln antibody (clone 32) was used in human HeLa cells and in western blot, immunoprecipitation to study the characterization of Gemin8 as a novel integral component of the SMN complex and the role for Gemin8 in small nuclear ribonucleoprotein assembly. more
total:5
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-Gemin3 antibody (sc-57007) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:4
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-Gemin2 antibody (sc-57006) was used to perform western blot, immunoprecipitation and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) monoclonal gemin 4 antibody was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
total:2
Regulation of SMN protein stability. 2009 to the paper
Abcam anti-Gemin 5 antibody was used to perform western blot in order to study the mechanism of the regulation towards the SMN Protein Stability. more
total:2
Regulation of SMN protein stability. 2009 to the paper
Abcam anti-Gemin 6 antibody was used to perform western blot in order to study the mechanism of the regulation towards the SMN Protein Stability. more
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) monoclonal gemin 7 antibody was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:2
Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation. 2009 to the paper
Upstate Biotech rabbit PRMT5 antibody was used for immunoprecipitation in order to explain how Blimp-1 silences the mature B-cell genes in plasma cell differentiation. more
total:32
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. 2010 to the paper
Sigma mouse-anti-SMN mAb was used to perform immunocytochemistry in order to clarify that TDP-43 transgenic and conditional knockout mouse models implicated a critical role of TDP-43 in pathways critical for motor neuron physiology and RNA processing. more
total:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-SmB/B' antibody (sc-271094) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Mercury mouse anti-2, 2, 7-trimethylguanosine (TMG)antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.