skin neoplasms
gene
reagent
sample publication
sample review
total:1
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. 2005 to the paper
Santa Cruz Biotechnology MC1R antibody (N-19) antibody was used in western blot and immunohistochemistry to study its expression in skin cancer abd red hair persons
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
total:6
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
Lab Vision MART1 antibody was used to perform western blot in order to further explore the relationship between Wnt5A and ROR2 more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:10
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D mouse anti-pTyr antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:6
Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma. 2009 to the paper
Dako anti-MUM-1/IRF4 antibody (clone:MUM1P) was used in immunohistochemistry to analyze the expression pattern of MUM1, bcl-6, and CD138 along with the association of EBV in 222 well-characterized cases of BL. more
total:2
Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL. 2005 to the paper
Upstate Biotechnology anti-Tyr (P) antibody 4G10 was used in western blot to study the binding of the intracellular Fas Ligand (FasL) domain to the adaptor protein PSTPIP which results in the cytoplasmic localization of FasL. more
total:3
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
Santa Cruz Biotechnology rabbit anti-Ptch-1 was used to perform immunocytochemistry in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:1
Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons. 2008 to the paper
Santa Cruz goat Sox10 antibody (1:50) was used in immunohistochemistry in order to demonstrate that Hand2 is a multifunctional DNA binding protein affecting differentiation and cell type-specific gene expression in neural crest-derived noradrenergic sympathetic ganglion neurons
total:24
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Millipore anti-human nestin antibody was used to perform immunohistochemistry in order to study NKCC1 modulation of glioma cell migration. more
total:3
Melanoma Inhibitory Activity (MIA) increases the invasiveness of pancreatic cancer cells. 2005 to the paper
Roche Diagnostic GmbH anti-MIA antibody (which was in ELISA kit) was used in human cells and in ELISA to study the effect of melanoma inhibitory activity (MIA) on the invasiveness of pancreatic cancer cells. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:3
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. 2008 to the paper
Lab Vision mouse monoclonal HMB45 antibody (1:100) was used in immunocytochemistry in order to study the role of Switch I region in the recruitment of Rab effector proteins. more
total:20
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB2 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:1
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Developmental Studies Hybridoma Bank mouse monoclonal anti-Pax3 antibody was used in flow cytometry at 1:50 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells
total:23
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
BD anti-mouse S100B antibody (1:1000) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:12
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-NG2 antibody (1:1500) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel monoclonal anti-FH antibody was used in ELISA to study the association of the extracellular matrix and inflammation
total:12
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD123 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:22
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD10 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:44
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Millipore anti-CDK4 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:26
Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation. 2014 to the paper
Santa Cruz Biotechnology anti-p63 antibody was used to perform immunohistochemistry in order to study TNFa/TNFR2 axis protective role for skin against DUOX1-mediated oxidative stress. more
total:79
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD34 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
total:11
Antimicrobial peptide hLF1-11 directs granulocyte-macrophage colony-stimulating factor-driven monocyte differentiation toward macrophages with enhanced recognition and clearance of pathogens. 2010 to the paper
BD Biosciences anti-CD163 monoclonal antibody was used to perform flow cytometry in order to study the antimicrobial peptide hLF1-11 affected human monocyte-macrophage differentiation. more
total:10
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
Immunotech/Coulter anti-CD30 antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:8
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB1 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
R&D Wnt5A antibody was used to perform western blot in order to investigate the effection of Wnt5A to ROR2 more
total:1
Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma. 2009 to the paper
Abcam anti-Gli2 antibody was used to perform immunohistochemistry in order to study the roles of Atoh1 in sonic hedgehog signaling during the development of cerebellum.
total:15
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Affinity BioReagents anti-VDR (MA1-7101, 1:400) monoclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder. more
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Calbiochem anti-Bim antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 to the paper
Novus Biologicals anti-p75NTR antibody was used to perform immunocytochemistry in order to show that cellular phenotype can be changed after exposure to acid and bile salt in Barrett's epithelial cell line. more
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:2
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. 2008 to the paper
Abcam rabbit anti-KLF4 antibody 1:15,000 was used for western blot in order to investigate the role of eIF4GI in the regulation of cell proliferation and autophagy. more
total:2
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-XPC antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:20
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Abcam anit-keratin 5 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:1
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-Nodal antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization.
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:129
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
AbCam anti-Ki67 was used to perform immunohistochemistry in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:14
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. 2008 to the paper
Santa Cruz Biotechnology anti-PDGFRA antibody was used to perform Western Blot and immunohistochemistry in order to prove that the metastatic behavior of human colorectal cancer correlates with PDGFRalpha/beta expression. more