recurrence
gene
reagent
sample publication
sample review
total:6
Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. 2006 to the paper
Santa Cruz Biotechnology anti-FLT3(S18) antibody was used to perform western blot in order to study the mechanism of the decreased proliferation of acute myeloid leukemia (AML) cells treated with arsenic trioxide. more
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
total:17
The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi. 2010 to the paper
NeoMarkers anti-WT1 antibody was used to carry out western blot analysis in order to investigate the regulation of apoptosis and the oncogenic activities of WT1 by HtrA2. more
total:4
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-RanBP2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
total:1
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion. 2008 to the paper
Santa Cruz Biotechnology TTP antibody was used in immunocytochemistry in order to study the mechanism of persistent translation arrest
total:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Affinity Biologicals sheep anti-factor V antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder. more
total:10
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. 2009 to the paper
Chemicon International rabbit polyclonal anti-VASP antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the roles of ADMA and DDAH in the regulation of pulmonary endothelial barrier function. more
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3a antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:21
C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters. 2009 to the paper
Affinity Bioreagents mouse anti-C/EBPa antibody was used to carry out immunoprecipitation assay and western blot analysis in order to investigate the mechanism for oncoprotein C/EBPa cooperated with NF-kB p50 to inhibit apoptosis. more
total:6
Regulation of corticotropin-releasing hormone receptor-2 expression in human cord blood-derived cultured mast cells. 2005 to the paper
Santa Cruz Biotechnology polyclonal goat anti-human/mouse/rat CRH-R1 antibody (V-14 sc-12381) was used in immunocytochemistry to study the expression of CRH-R1 and CRH-R2 n human cord blood-derived cultured mast cells. more
total:5
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
BD Bioscience anti-PSGL-1 antibody (PL1) was used in blocking or activating expriments to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
total:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 to the paper
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death. more
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
total:17
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Upstate Biotechnology mouse anti-CFTR antibody (clone M3A7) was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
total:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 to the paper
Invitrogen Purified goat IgG was used as the isotypic controls in order to identify the MHC I molecule (HLA-C) as an attachment factor in facilitating HCoV-HKU1 spike (S) mediated infection. more
total:1
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Lifespan Biosciences anti-IDH1 antibody was used to perform western blot in order to study the function of quiescent fibroblasts.
total:1
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. 2011 to the paper
Abcam rabbit anti-Foxp1 antibody(1:100)was used to perform immunocytochemistry in order to investigate the role of retinoic acid in generation of GABAergic neurons in the basal ganglia.
total:7
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 to the paper
R&D Systems anti-human IL-15R antibody was used to perform enzyme-linked immunosorbent assays in order to investigate the relationship between IL-15R and specific immune response. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:8
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 to the paper
Hycult-Biotechnologies anti-CD46 mouse monoclonal antibody was used to perform western blot and flow cytometry in order to study the function of CD147/EMMPRIN as a receptor for measles virus on epithelial cells. more
total:1
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms. 2009 to the paper
Sigma rabbit anti-Podocin antibody was used to perform immunohistochemistry in order to study the role of the universal polarity protein, aPKC Lambda.
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:4
High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. 2006 to the paper
Sanquin biotinylated mouse-anti-MBL IgG 5E12 (10 ug/ml) was used in ELISA assay as the detection antibody to measure MBL in plasma to study the high prevalence of mannose-binding lectin (MBL) deficiency in premature neonates more
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:34
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
Upstate anti-JAK2 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:18
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. 2008 to the paper
DAKO polyclonal anti-PSA antibody was used in immunohistochemistry in order to investigate mechanisms by which advanced prostate cancers maintain AR-mediated gene expression following castration more
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:11
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. 2009 to the paper
Chemicon International antibodies against BDNF was used in immunohistochemistry in order to confirm the differential expression of neurotrophins in postnatal C57BL/6 mice striatum. more
total:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 to the paper
Cayman Chemical NOD2-specific rabbit antiserum was used in immunoprecipitation and western blot to measure its expression in primary keratinocytes and transfected HEK293 cells. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:10
Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. 2008 to the paper
Santa Cruz Biotechnology anti-AQP4 antibody (H-80) was used in immunohistochemistry to investigate AQP4 expression in cerebral cortex from AD patients. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:6
Expression and location of alpha-fetoprotein during rat colon development. 2009 to the paper
Santa Cruz Biotechnology goat polyclonal anti-AFP antibody was used to carry out western blot analysis in order to invesitgate the expression and location of AFP protein in rat developmental colon. more
total:9
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR3 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
total:129
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
AbCam anti-Ki67 was used to perform immunohistochemistry in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:3
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 to the paper
Sigma rabbit polyclonal anti-RUNX1 antibody was used in immunocytochemistry to study the interaction between E4orf6, E1B-55K, and RUNX1 and the association of the RUNX1 with centers of viral DNA and RNA synthesis. more
total:1
Development of sandwich-type ELISAs for the quantification of rat and murine thrombin activatable fibrinolysis inhibitor in plasma. 2008 to the paper
A. GILS (Katholieke Universiteit Leuven) TAFI antibody was used in elisa to develope an ELISA for the quantification of rat and murine TAFI in plasma.
total:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 to the paper
Santa Cruz anti-CTLA-4 antibody was used to perform immunocytochemistry in order to reveal the reason why CTLA-4 can inhibit CD28 stimulation. more
total:10
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Neomarkers anti-MUC5AC antibody was used to perform western blot and immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:11
Role of copper and homocysteine in pressure overload heart failure. 2008 to the paper
Santa Cruz Biotechnology TIMP3 antibody was used in western blot in order to investigate the role of copper and homocysteine in pressure overload heart failure more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:5
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
BD anti-pan-MCM antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:3
Immortalization and characterization of lineage-restricted neuronal progenitor cells derived from the porcine olfactory bulb. 2008 to the paper
Abcam rabbit anti-neuregulin-1 antibody (1:100) was used in immunocytochemistry in order to study the role of CCR5 in the migration of pulmonary fibrocytes and the promotion of metastasis more
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:79
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD34 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:38
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-iNOS antibody was used in western blot to study the role for elevated arginase expression in HCV associated HCC more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
total:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
PharMingen anti-HLA-B antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 to the paper
Santa Cruz Biotechnology anti-HLA-A(A-18) antibody was used to perform immunohistochemistry in order to study tumor and tumor-stromal cell interactions. more
total:52
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 to the paper
Upstate anti-AR (PG-21) antibody was used to perform ChIP in order to study the rational drug design for castration-resistant prostate cancer without mutation-based resistance to antiandrogens. more
total:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 to the paper
Alexis rabbit polyclonal anti-Nalp3 antibody (which recognizes WT, R260W, and D303N cryopyrins) was used in human cells and in immunocytochemistry to study the role of cryopyrin and pyrin in activating caspase-1.
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
BD Gentest anti-CYP2C9 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:2
Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice. 2007 to the paper
Immunostar 5-HTT antibody was used in western blot and immunohistochemistry to study the role of GAP-43 in regulating neurotransmitter release. more